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公开(公告)号：US4083969A
公开(公告)日：1978-04-11
申请号：US674432
申请日：1976-04-07
CPC分类号： A61K31/704 , A61K47/32 , A61K47/36 , A61K47/38 , A61K9/146
摘要： Sterol glycosides are rendered easily absorbable through the digestive tract by dissolving or dispersing the steroid glycoside with heating into a water solution of a polymer or polymers and then removing the solvent.
摘要翻译： 甾醇糖苷通过将甾类糖苷加热溶解或分散到聚合物或聚合物的水溶液中并通过消化道容易地吸收，然后除去溶剂。
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2.发明授权Process for producing easily absorbable amorphous steryl glucoside monopalmitates and preparations thereof 失效制备容易吸收的无定形固醇葡糖苷单棕榈酸酯及其制备方法
公开(公告)号：US4129649A
公开(公告)日：1978-12-12
申请号：US683478
申请日：1976-05-05
IPC分类号： A61K9/14 , C07J17/00 , A61K31/705 , C07G3/00
CPC分类号： C07J17/005
摘要： A process for producing amorphous preparations of steryl glucoside monopalmitates, wherein steryl glucoside monopalmitates are heated at a temperature above 110.degree. C up to about 145.degree. C or the compounds are dissolved in an organic solvent in which they are soluble with a solvent which is then distilled off, and the compounds then pulverized and mixed with physiologically harmless organic or inorganic fine particles in a proportion of 0.5 times (by weight) of the compounds or more, thereby homogeneously dispersing the amorphous compounds in the fine particles or uniformtly adsorbing the compounds on the fine particles, and the resulting preparations which have hemostatic properties and are readily absorbable upon ingestion. The starting steryl glucoside monopalmitates are obtained in crystalline form as from soy beans or other vegetable sources.
摘要翻译： 制备甾醇葡糖苷单棕榈酸酯的无定形制剂的方法，其中将甾醇葡糖苷单棕榈酸酯在高于110℃的温度下加热至约145℃，或将化合物溶于其中可溶于溶剂的有机溶剂中， 蒸馏除去，然后将化合物与生理上无害的有机或无机细颗粒以0.5重量份以上的比例进行粉碎和混合，从而将无定形化合物均匀分散在细颗粒中或均匀地吸附化合物 细颗粒以及所得到的具有止血性并且在摄入时容易吸收的制剂。 从大豆或其他植物来源获得结晶形式的起始固体葡糖苷单棕榈酸酯。
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3.发明授权2-Aminomethyl-5-phenyloxazoles and the pharmaceutically acceptable salts thereof 失效2-氨基甲基-5-苯基恶唑及其药学上可接受的盐
公开(公告)号：US4123541A
公开(公告)日：1978-10-31
申请号：US839354
申请日：1977-10-04
申请人： Sho Inoue , Katsuya Ohata , Satoshi Tsutsui , Tatsuo Nomura
发明人： Sho Inoue , Katsuya Ohata , Satoshi Tsutsui , Tatsuo Nomura
IPC分类号： C07D263/32 , A61K31/42
CPC分类号： C07D263/32
摘要： 2-Aminomethyl-5-phenyloxazoles and the pharmaceutically acceptacle salts thereof have been found to be effective for meliorating inflammation in warm blooded animals.
摘要翻译： 已经发现2-氨基甲基-5-苯基恶唑及其药学上可接受的盐对于改善温血动物的炎症是有效的。
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公开(公告)号：US4112218A
公开(公告)日：1978-09-05
申请号：US746940
申请日：1976-12-02
申请人： Sho Inoue , Akira Sano , Koji Kitaguchi
发明人： Sho Inoue , Akira Sano , Koji Kitaguchi
CPC分类号： C07J17/005
摘要： Sterol glycosides are isolated from sterol glycoside-containing plant material by heating the material in alkaline lower alkanol at elevated temperatures in the presence of an alkali metal carbonate, bicarbonate or nitrate to effect formation and precipitation of a complex which is then isolated.
摘要翻译： 通过在碱金属碳酸盐，碳酸氢盐或硝酸盐的存在下，在升高的温度下加热碱性低级链烷醇中的物质，从固体糖苷植物材料中分离甾醇糖苷，以形成并沉淀出复合物，然后分离。
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5.发明授权2-Aminomethyl-5-phenyloxazoles and the pharmaceutically acceptable acid addition salts thereof 失效2-氨基甲基-5-苯基恶唑及其药学上可接受的酸加成盐
公开(公告)号：US4101660A
公开(公告)日：1978-07-18
申请号：US766975
申请日：1977-02-09
申请人： Sho Inoue , Katsuya Ohata , Satoshi Tsutsui , Tatsuo Nomura
发明人： Sho Inoue , Katsuya Ohata , Satoshi Tsutsui , Tatsuo Nomura
IPC分类号： C07D263/32 , A61K31/495 , C07D413/06
CPC分类号： C07D263/32
摘要： 2-Aminomethyl-5-phenyloxazoles and the pharmaceutically acceptable salts thereof have been found to be effective for meliorating inflammation in warm blooded animals.
摘要翻译： 已经发现2-氨基甲基-5-苯基恶唑及其药学上可接受的盐对于改善温血动物的炎症是有效的。
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