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公开(公告)号：US20130180012A1
公开(公告)日：2013-07-11
申请号：US13640488
申请日：2011-04-11
申请人： Shoshana Arad , Lena Plesser , Yaakov Weinstein
发明人： Shoshana Arad , Lena Plesser , Yaakov Weinstein
IPC分类号： C12N9/10
CPC分类号： C12N9/13 , C07K14/405 , C12N9/10 , C12N15/8243 , C12P11/00 , C12P19/04 , Y02P20/52
摘要： An isolated protein which is at least partially encoded by a polynucleotide sequence encoding a novel sulfotransferase is provided together with a composition which includes the isolated protein. A transgenic organism transformed by a polynucleotide encoding a protein which is at least partially encoded by a novel sulfotransferase is also provided. The invention also includes a process for in-vivo and in-vitro making a sulfated polysaccharide from an unsulfated polysaccharide or increasing the sulfur content of an already sulfated polysaccharide.
摘要翻译： 与编码新型磺基转移酶的多核苷酸序列至少部分编码的分离蛋白与包含分离的蛋白质的组合物一起提供。 还提供了由编码至少部分由新型磺基转移酶编码的蛋白质的多核苷酸转化的转基因生物体。 本发明还包括用于体内和体外制备来自未硫酸化多糖的硫酸化多糖或增加已硫酸化多糖的硫含量的方法。
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公开(公告)号：US09458438B2
公开(公告)日：2016-10-04
申请号：US13640488
申请日：2011-04-11
申请人： Shoshana Arad , Lena Plesser , Yaakov Weinstein
发明人： Shoshana Arad , Lena Plesser , Yaakov Weinstein
IPC分类号： C12N9/10 , C12N15/82 , C12P11/00 , C07K14/405 , C12P19/04
CPC分类号： C12N9/13 , C07K14/405 , C12N9/10 , C12N15/8243 , C12P11/00 , C12P19/04 , Y02P20/52
摘要： An isolated protein which is at least partially encoded by a polynucleotide sequence encoding a novel sulfotransferase is provided together with a composition which includes the isolated protein. A transgenic organism transformed by a polynucleotide encoding a protein which is at least partially encoded by a novel sulfotransferase is also provided. The invention also includes a process for in-vivo and in-vitro making a sulfated polysaccharide from an unsulfated polysaccharide or increasing the sulfur content of an already sulfated polysaccharide.
摘要翻译： 与编码新型磺基转移酶的多核苷酸序列至少部分编码的分离蛋白与包含分离的蛋白质的组合物一起提供。 还提供了由编码至少部分由新型磺基转移酶编码的蛋白质的多核苷酸转化的转基因生物体。 本发明还包括用于体内和体外制备来自未硫酸化多糖的硫酸化多糖或增加已硫酸化多糖的硫含量的方法。
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