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1.发明公开公开(公告)号：US20230158035A1
公开(公告)日：2023-05-25
申请号：US18095670
申请日：2023-01-11
发明人： Matthew Alexander , Sogole Bahmanyar , John Frederick Boylan , Joshua Hansen , Dehua Huang , Robert Hubbard , Brandon Jeffy , Jim Leisten , Mehran Moghaddam , Raj K. Raheja , Heather Raymon , Kimberly Schwarz , Marianne Sloss , Eduardo Torres , Tam Minh Tran , Shuichan Xu , Jingjing Zhao
IPC分类号： A61K31/52 , C07D473/32 , A61P35/00 , A61K31/5377
CPC分类号： A61K31/52 , C07D473/32 , A61P35/00 , A61K31/5377
摘要： Provided herein are Aminopurine Compounds having the following structures:
wherein R1, R2, and R3 are as defined herein, compositions comprising an effective amount of an Aminopurine Compound, and methods for treating or preventing a cancer, for example, melanoma.-
2.发明授权公开(公告)号：US10576085B2
公开(公告)日：2020-03-03
申请号：US15475899
申请日：2017-03-31
发明人： John F. Boylan , Gordon L. Bray , Ellen Filvaroff , Robert Hubbard , David Mikolon , Heather Raymon , Tao Shi , Tam M. Tran , Toshiya Tsuji , Lilly L. Wong , Shuichan Xu , Dan Zhu
IPC分类号： A61K31/52
摘要： Provided herein are methods for treating or preventing a cancer, including solid tumors and hematological cancers, comprising administering an effective amount of aminopurine compounds of formula (I), and compositions comprising an effective amount of such compounds.
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3.发明申请公开(公告)号：US20210128565A1
公开(公告)日：2021-05-06
申请号：US17147127
申请日：2021-01-12
发明人： Matthew Alexander , Sogole Bahmanyar , John Frederick Boylan , Joshua Hansen , Dehua Huang , Robert Hubbard , Brandon Jeffy , Jim Leisten , Mehran Moghaddam , Raj K. Raheja , Heather Raymon , Kimberly Schwarz , Marianne Sloss , Eduardo Torres , Tam Minh Tran , Shuichan Xu , JingJing Zhao
IPC分类号： A61K31/52 , C07D473/32 , A61P35/00 , A61K31/5377
摘要： Provided herein are Aminopurine Compounds having the following structures: wherein R1, R2, and R3 are as defined herein, compositions comprising an effective amount of an Aminopurine Compound, and methods for treating or preventing a cancer, for example, melanoma.
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4.发明申请公开(公告)号：US20200237768A1
公开(公告)日：2020-07-30
申请号：US16846503
申请日：2020-04-13
发明人： Matthew Alexander , Sogole Bahmanyar , John Frederick Boylan , Joshua Hansen , Dehua Huang , Robert Hubbard , Brandon Jeffy , Jim Leisten , Mehran Moghaddam , Raj K. Raheja , Heather Raymon , Kimberly Schwarz , Marianne Sloss , Eduardo Torres , Tam Minh Tran , Shuichan Xu , JingJing Zhao
IPC分类号： A61K31/52 , A61K31/5377 , A61P35/00 , C07D473/32
摘要： Provided herein are Aminopurine Compounds having the following structures: wherein R1, R2, and R3 are as defined herein, compositions comprising an effective amount of an Aminopurine Compound, and methods for treating or preventing a cancer, for example, melanoma.
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5.发明授权公开(公告)号：US10398700B2
公开(公告)日：2019-09-03
申请号：US16169414
申请日：2018-10-24
发明人： Matthew Alexander , Joshua Hansen , Dehua Huang , Robert Hubbard , Raj K. Raheja , Kimberly Schwarz , Marianne Sloss , Eduardo Torres , JingJing Zhao
IPC分类号： A61K31/52 , C07D473/32 , A61K31/5377 , A61P35/00
摘要： Provided herein are Aminopurine Compounds having the following structures: wherein R1, R2, and R3 are as defined herein, compositions comprising an effective amount of an Aminopurine Compound, and methods for treating or preventing a cancer, for example, melanoma.
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6.发明申请公开(公告)号：US20170296546A1
公开(公告)日：2017-10-19
申请号：US15641383
申请日：2017-07-05
发明人： Matthew Alexander , Joshua Hansen , Dehua Huang , Robert Hubbard , Raj K. Raheja , Kimberly Schwarz , Marianne Sloss , Eduardo Torres , JingJing Zhao
IPC分类号： A61K31/52 , C07D473/32 , A61K31/5377
CPC分类号： A61K31/52 , A61K31/5377 , A61P35/00 , C07D473/32
摘要： Provided herein are Aminopurine Compounds having the following structures: wherein R1, R2, and R3 are as defined herein, compositions comprising an effective amount of an Aminopurine Compound, and methods for treating or preventing a cancer, for example, melanoma.
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7.发明授权公开(公告)号：US10646493B2
公开(公告)日：2020-05-12
申请号：US16514749
申请日：2019-07-17
发明人： Matthew Alexander , Sogole Bahmanyar , John Frederick Boylan , Joshua Hansen , Dehua Huang , Robert Hubbard , Brandon Jeffy , Jim Leisten , Mehran Moghaddam , Raj K. Raheja , Heather Raymon , Kimberly Schwarz , Marianne Sloss , Eduardo Torres , Tam Minh Tran , Shuichan Xu , JingJing Zhao
IPC分类号： A61K31/52 , C07D473/32 , A61P35/00 , A61K31/5377
摘要： Provided herein are Aminopurine Compounds having the following structures: wherein R1, R2, and R3 are as defined herein, compositions comprising an effective amount of an Aminopurine Compound, and methods for treating or preventing a cancer, for example, melanoma.
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8.发明申请公开(公告)号：US20190336507A1
公开(公告)日：2019-11-07
申请号：US16514749
申请日：2019-07-17
发明人： Matthew Alexander , Joshua Hansen , Dehua Huang , Robert Hubbard , Raj K. Raheja , Kimberly Schwarz , Marianne Sloss , Eduardo Torres , JingJing Zhao , Shuichan Xu , Sogole Bahmanyar
IPC分类号： A61K31/52 , A61P35/00 , C07D473/32 , A61K31/5377
摘要： Provided herein are Aminopurine Compounds having the following structures: wherein R1, R2, and R3 are as defined herein, compositions comprising an effective amount of an Aminopurine Compound, and methods for treating or preventing a cancer, for example, melanoma.
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9.发明授权公开(公告)号：US09737541B2
公开(公告)日：2017-08-22
申请号：US15335619
申请日：2016-10-27
发明人： Matthew Alexander , Sogole Bahmanyar , Joshua Hansen , Dehua Huang , Robert Hubbard , Brandon Jeffy , Jim Leisten , Mehran Moghaddam , Raj K. Raheja , Heather Raymon , Kimberly Schwarz , Marianne Sloss , Eduardo Torres , Tam Minh Tran , Shuichan Xu , JingJing Zhao , John Frederick Boylan
IPC分类号： C07D473/32 , A61K31/52 , A61K31/5377
CPC分类号： A61K31/52 , A61K31/5377 , A61P35/00 , C07D473/32
摘要： Provided herein are Aminopurine Compounds having the following structures: wherein R1, R2, and R3 are as defined herein, compositions comprising an effective amount of an Aminopurine Compound, and methods for treating or preventing a cancer, for example, melanoma.
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10.发明申请SUBSTITUTED AMINOPURINE COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH 审中-公开取代的氨基嘌呤化合物，其组合物及其处理方法公开(公告)号：US20170042902A1
公开(公告)日：2017-02-16
申请号：US15335619
申请日：2016-10-27
发明人： Matthew Alexander , Sogole Bahmanyar , Joshua Hansen , Dehua Huang , Robert Hubbard , Brandon Jeffy , Jim Leisten , Mehran Moghaddam , Raj K. Raheja , Heather Raymon , Kimberly Schwarz , Marianne Sloss , Eduardo Torres , Tam Minh Tran , Shuichan Xu , JingJing Zhao , John Frederick Boylan
IPC分类号： A61K31/52 , A61K31/5377
CPC分类号： A61K31/52 , A61K31/5377 , A61P35/00 , C07D473/32
摘要： Provided herein are Aminopurine Compounds having the following structures: wherein R1, R2, and R3 are as defined herein, compositions comprising an effective amount of an Aminopurine Compound, and methods for treating or preventing a cancer, for example, melanoma.
摘要翻译： 本文提供具有以下结构的氨基嘌呤化合物：其中R1，R2和R3如本文所定义，包含有效量的氨基嘌呤化合物的组合物，以及用于治疗或预防癌症的方法，例如黑素瘤。
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