公开(公告)号：US20180303886A1

公开(公告)日：2018-10-25

申请号：US15738034

申请日：2016-06-17

申请人： SillaJen, Inc.

发明人： Tae Ho HWANG ,  Nam Hee LEE ,  Mong CHO ,  Ungbae JEON ,  Doo Jin BYUN

IPC分类号： A61K35/768 ,  A61K9/00 ,  A61K47/42 ,  A61P35/00 ,  C12N7/00

摘要： The present disclosure relates to oncolytic viruses for use transcatheter arterial viroembolization methods. The present disclosure also provides composition with such oncolytic viruses in combination with a biocompatible microparticle or hydrophilic polymer gel agent suitable for active embolization. The present disclosure further provides methods of transcatheter arterial viroembolization using such oncolytic viruses and compositions preferably in a manner that debulks tumor.