公开(公告)号：US20050124574A1

公开(公告)日：2005-06-09

申请号：US11042582

申请日：2005-01-24

申请人： Simon Mantell ,  Sandra Monaghan

发明人： Simon Mantell ,  Sandra Monaghan

IPC分类号： C07H19/167 ,  A61K31/7076 ,  A61P1/00 ,  A61P1/04 ,  A61P3/10 ,  A61P9/10 ,  A61P9/12 ,  A61P9/14 ,  A61P11/00 ,  A61P11/02 ,  A61P11/06 ,  A61P15/10 ,  A61P17/00 ,  A61P17/02 ,  A61P17/04 ,  A61P17/06 ,  A61P25/00 ,  A61P25/08 ,  A61P27/16 ,  A61P29/00 ,  A61P31/04 ,  A61P37/08 ,  A61P43/00 ,  C07H19/16

CPC分类号： C07H19/16

摘要： The present invention relates to compounds of the formula and pharmaceutically acceptable salts and solvates thereof, and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such compounds as adenosine A2a receptor agonists.

公开(公告)号：US20060014780A1

公开(公告)日：2006-01-19

申请号：US11229395

申请日：2005-09-16

申请人： Simon Bailey ,  Elisabeth Gautier ,  Alan Henderson ,  Thomas Magee ,  Anthony Marfat ,  John Mathias ,  Dale McLeod ,  Sandra Monaghan ,  Blanda Stammen

发明人： Simon Bailey ,  Elisabeth Gautier ,  Alan Henderson ,  Thomas Magee ,  Anthony Marfat ,  John Mathias ,  Dale McLeod ,  Sandra Monaghan ,  Blanda Stammen

IPC分类号： A61K31/46 ,  A61K31/4545 ,  A61K31/4433 ,  A61K31/4415 ,  C07D405/02 ,  C07D401/02 ,  C07D453/02

CPC分类号： C07D213/82 ,  A61K31/4433 ,  A61K31/455 ,  A61K31/46 ,  A61K31/537 ,  A61K45/06 ,  C07D401/12 ,  C07D405/12 ,  C07D451/04 ,  C07D451/10 ,  Y02A50/411 ,  A61K2300/00

摘要： The invention relates to nicotinamide derivatives and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. The nicotinamide derivatives according to the present invention are useful in numerous diseases, disorders and conditions, in particular inflammatory, allergic, respiratory diseases, disorders and conditions, as well as wounds.