公开(公告)号：US11845923B2

公开(公告)日：2023-12-19

申请号：US17369593

申请日：2021-07-07

Applicant: Singular Genomics Systems, Inc.

Inventor： Souad Naji ,  Carl W. Fuller ,  Eli Glezer ,  Andrew Spaventa

IPC: C12N9/12 ,  C12P19/34

CPC classification number: C12N9/1252 ,  C12P19/34 ,  C12Y207/07007

Abstract: Provided herein are modified Archaeal family B polymerases derived from the Archaeal microorganism Pyrococcus abyssi that exhibit improved incorporation of nucleotide analogues utilized in DNA sequencing.

公开(公告)号：US11136565B2

公开(公告)日：2021-10-05

申请号：US16568089

申请日：2019-09-11

Applicant: Singular Genomics Systems, Inc.

Inventor： Souad Naji ,  Carl W. Fuller ,  Eli Glezer ,  Andrew Spaventa

IPC: C12N9/12 ,  C12P19/34

Abstract: Provided herein are modified Archaeal family B polymerases derived from the Archaeal microorganism Pyrococcus abyssi that exhibit improved incorporation of nucleotide analogues utilized in DNA sequencing.

公开(公告)号：US20240101979A1

公开(公告)日：2024-03-28

申请号：US18500785

申请日：2023-11-02

Applicant: Singular Genomics Systems, Inc.

Inventor： Souad Naji ,  Carl W. Fuller ,  Eli N. Glezer ,  Andrew Spaventa

IPC: C12N9/12 ,  C12P19/34

CPC classification number: C12N9/1252 ,  C12P19/34 ,  C12Y207/07007

Abstract: Provided herein are modified Archaeal family B polymerases derived from the Archaeal microorganism Pyrococcus abyssi that exhibit improved incorporation of nucleotide analogues utilized in DNA sequencing.

公开(公告)号：US11512295B2

公开(公告)日：2022-11-29

申请号：US17017578

申请日：2020-09-10

Applicant: Singular Genomics Systems, Inc.

Inventor： Souad Naji ,  Carl W. Fuller ,  Eli N. Glezer ,  Andrew Spaventa

IPC: C12N9/12 ,  C12N15/10 ,  C12Q1/6874

Abstract: Provided herein are modified Archaeal family B polymerases derived from the Archaeal microorganism Thermococcus sp. EP1 that exhibit improved incorporation of nucleotide analogues utilized in DNA sequences.

公开(公告)号：US12110515B2

公开(公告)日：2024-10-08

申请号：US18048388

申请日：2022-10-20

Applicant: Singular Genomics Systems, Inc.

Inventor： Souad Naji ,  Carl W. Fuller ,  Eli N. Glezer ,  Andrew Spaventa

IPC: C12N9/12 ,  C12N15/10 ,  C12Q1/6874

CPC classification number: C12N9/1252 ,  C12N15/102 ,  C12Q1/6874 ,  C12Y207/07007

Abstract: Provided herein are modified Archaeal family B polymerases derived from the Archaeal microorganism Thermococcus sp. EP1 that exhibit improved incorporation of nucleotide analogues utilized in DNA sequences.