公开(公告)号：US12000071B2

公开(公告)日：2024-06-04

申请号：US17595549

申请日：2020-06-12

Applicant: Solventum Intellectual Properties Company

Inventor： Petra L. Kohler Reidi ,  Saurabh Batra ,  Hannah C. Cohen ,  Semra Colak Atan ,  Naimul Karim ,  Joseph J. Stoffel ,  Joseph A. Dunbar ,  Colby W. Dotseth

IPC: D04H1/56 ,  D01F6/34 ,  D01F8/10 ,  D04H1/4258 ,  D04H1/4291 ,  D04H1/4309

CPC classification number: D04H1/56 ,  D01F6/34 ,  D01F8/10 ,  D04H1/4258 ,  D04H1/4291 ,  D04H1/4309

Abstract: A method of making a nonwoven fiber web comprises: providing a melt-blown nonwoven fiber web comprising bonded primary fibers having an average fiber diameter of 2 to 100 microns, wherein the primary fibers comprise a copolymer comprising divalent hydroxyethylene monomer units and divalent dihydroxybutylene monomer units; opening at least a portion of the melt-blown nonwoven fiber web to provide loose primary fibers; combining the loose primary fibers with secondary fibers; and forming a secondary nonwoven fiber web comprising the primary fibers and secondary fibers. A fiber web preparable according to the method and a multicomponent fiber including a first phase comprising a copolymer comprising divalent hydroxyethylene monomer units and divalent dihydroxybutylene monomer units and a second phase comprising a non-biodegradable polymer.

公开(公告)号：US20250011845A1

公开(公告)日：2025-01-09

申请号：US18707776

申请日：2022-11-04

Applicant: Solventum Intellectual Properties Company

Inventor： Annabelle Watts ,  Tonya D. Bonilla ,  Jerald K. Rasmussen ,  Joshua M. Fishman ,  Lindsay L. Traeger ,  Semra Colak Atan

IPC: C12Q1/6834 ,  C12N15/10 ,  C12Q1/6806 ,  C12Q1/686 ,  G01N27/447

Abstract: A method of processing polynucleic acids is described comprising: providing a solid support comprising ligands with an amide group: exposing the solid support to polynucleic acid molecules in a buffer having a pH less than 5.5 to bind at least a portion of the polynucleic acid molecules to the ligands: c) exposing the solid support (e.g. particles) with bound polynucleic acid molecules to a buffer having a pH greater than 6 to release a portion of the bound polynucleic acid molecules from the ligands of the particles and to retain a portion of the polynucleic acid molecules bound to the solid support (e.g. particles); and utilizing the solid support with retained bound polynucleic acid molecules or suspension thereof.