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公开(公告)号:US20240116972A1
公开(公告)日:2024-04-11
申请号:US18510128
申请日:2023-11-15
申请人: Southern Research Institute , Oregon Health & Science University , Washington University in St. Louis , Board of Regents, The University of Texas System
发明人: Omar Moukha-Chafiq , Ashish Kumar Pathak , Shuklendu D. Karyakarte , Larry D. Bratton , Corinne E. Augelli-Szafran , Michael Diamond , Pei Yong Shi , Alec Jay Hirsch , Jessica Lee Smith , Daniel Streblow , Nicole Haese , Baoling Ying
摘要: The present disclosure is concerned with 6-aza-nucleoside prodrugs that are capable of inhibiting a viral infection and methods of treating viral infections such as, for example, human immunodeficiency virus (HIV), human papillomavirus (HPV), chicken pox, infectious mononucleosis, mumps, measles, rubella, shingles, ebola, viral gastroenteritis, viral hepatitis, viral meningitis, human metapneumovirus, human parainfluenza virus type 1, parainfluenza virus type 2, parainfluenza virus type 3, respiratory syncytial virus, viral pneumonia, yellow fever virus, tick-borne encephalitis virus, Chikungunya virus (CHIKV), Venezuelan equine encephalitis (VEEV), Eastern equine encephalitis (EEEV), Western equine encephalitis (WEEV), dengue (DENV), influenza, West Nile virus (WNV), zika (ZIKV), Middle East Respiratory Syndromes (MERS), Severe Acute Respiratory Syndrome (SARS), and coronavirus disease 2019 (COVID-19), using these compounds. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
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公开(公告)号:US11858956B2
公开(公告)日:2024-01-02
申请号:US17554979
申请日:2021-12-17
申请人: Southern Research Institute , Oregon Health & Science University , Washington University in St. Louis , Board of Regents, The University of Texas System
发明人: Omar Moukha-Chafiq , Ashish Kumar Pathak , Shuklendu D. Karyakarte , Larry D. Bratton , Corinne E. Augelli-Szafran , Michael Diamond , Pei Yong Shi , Alec Jay Hirsch , Jessica Lee Smith , Daniel Streblow , Nicole Haese , Baoling Ying
摘要: The present disclosure is concerned with 6-aza-nucleoside prodrugs that are capable of inhibiting a viral infection and methods of treating viral infections such as, for example, human immunodeficiency virus (HIV), human papillomavirus (HPV), chicken pox, infectious mononucleosis, mumps, measles, rubella, shingles, ebola, viral gastroenteritis, viral hepatitis, viral meningitis, human metapneumovirus, human parainfluenza virus type 1, parainfluenza virus type 2, parainfluenza virus type 3, respiratory syncytial virus, viral pneumonia, yellow fever virus, tick-borne encephalitis virus, Chikungunya virus (CHIKV), Venezuelan equine encephalitis (VEEV), Eastern equine encephalitis (EEEV), Western equine encephalitis (WEEV), dengue (DENV), influenza, West Nile virus (WNV), zika (ZIKV), Middle East Respiratory Syndromes (MERS), Severe Acute Respiratory Syndrome (SARS), and coronavirus disease 2019 (COVID-19), using these compounds. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
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公开(公告)号:US20220204545A1
公开(公告)日:2022-06-30
申请号:US17554979
申请日:2021-12-17
申请人: Southern Research Institute , Oregon Health & Science University , Washington University in St. Louis , Board of Regents of the University of Texas System and Its Component Institution University of Texas
发明人: Omar Moukha-Chafiq , Ashish Kumar Pathak , Shuklendu D. Karyakarte , Larry D. Bratton , Corinne E. Augelli-Szafran , Michael Diamond , Pei Yong Shi , Alec Jay Hirsch , Jessica Lee Smith , Daniel Streblow , Nicole Haese , Baoling Ying
摘要: The present disclosure is concerned with 6-aza-nucleoside prodrugs that are capable of inhibiting a viral infection and methods of treating viral infections such as, for example, human immunodeficiency virus (HIV), human papillomavirus (HPV), chicken pox, infectious mononucleosis, mumps, measles, rubella, shingles, ebola, viral gastroenteritis, viral hepatitis, viral meningitis, human metapneumovirus, human parainfluenza virus type 1, parainfluenza virus type 2, parainfluenza virus type 3, respiratory syncytial virus, viral pneumonia, yellow fever virus, tick-borne encephalitis virus, Chikungunya virus (CHIKV), Venezuelan equine encephalitis (VEEV), Eastern equine encephalitis (EEEV), Western equine encephalitis (WEEV), dengue (DENV), influenza, West Nile virus (WNV), zika (ZIKV), Middle East Respiratory Syndromes (MERS), Severe Acute Respiratory Syndrome (SARS), and coronavirus disease 2019 (COVID-19), using these compounds. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
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