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公开(公告)号：US20240398220A1
公开(公告)日：2024-12-05
申请号：US18697137
申请日：2022-09-12
Applicant: Spiral Therapeutics Inc.
Inventor： Signe Erickson , Vrad Levering , Eugene de Juan
Abstract: Systems and methods can be employed for trans-tympanic membrane access to the middle ear for delivery of a therapeutic agent, for example, to the round window niche adjacent to the cochlea under direct visualization. The systems and methods can also be used to improve accessibility and visualization for various other otological surgical procedures.
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公开(公告)号：US11906719B2
公开(公告)日：2024-02-20
申请号：US17155589
申请日：2021-01-22
Applicant: Spiral Therapeutics Inc.
Inventor： Eugene de Juan , Hugo Peris , Signe Erickson , Vrad Levering
IPC: A61B1/227 , A61B1/018 , G02B21/00 , G02B21/22 , A61B17/29 , A61M31/00 , A61B17/34 , A61M37/00 , A61B17/32 , A61B18/04 , A61B18/20 , A61F2/958 , A61B17/3205 , A61B18/14 , A61F11/20 , A61B17/00 , A61B18/00 , A61F2/18
CPC classification number: G02B21/0012 , A61B1/018 , A61B1/227 , A61B17/29 , A61B17/3205 , A61B17/320068 , A61B17/3423 , A61B17/3468 , A61B17/3478 , A61B18/04 , A61B18/1485 , A61B18/20 , A61F2/958 , A61F11/20 , A61F11/202 , A61M31/00 , A61M31/002 , A61M37/0015 , G02B21/0032 , G02B21/22 , A61B2017/00115 , A61B2017/00787 , A61B2017/00867 , A61B2017/32007 , A61B2018/00327 , A61B2217/005 , A61F2002/183 , A61F2250/0067 , A61M2037/0023 , A61M2037/0046 , A61M2205/04 , A61M2210/0662 , A61M2210/0668
Abstract: Systems and methods can be employed for trans-tympanic membrane access to the middle ear for delivery of a formulation or implant device to a target location under direct visualization. The systems and methods can also be used to improve accessibility and visualization for various otological surgical procedures, such as, but not limited to, cholesteatoma removal, tympanic membrane repair and ossicular chain repair.
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公开(公告)号：US20210228849A1
公开(公告)日：2021-07-29
申请号：US17155564
申请日：2021-01-22
Applicant: Spiral Therapeutics Inc.
Inventor： Eugene de Juan , Signe Erickson , Charles Limb , Hugo Peris , Nikhil Talreja , Andrew Ayoob
Abstract: Intra-tympanic injections of therapeutics into the inner ear can be used to treat conditions such as hearing loss. One or more stabilizing devices that define working channels can be temporarily implanted in the tympanic membrane. Purpose-built instruments such as endoscopes, forceps, and injections instruments can be passed through the working channels of the stabilizer devices to access the inner ear where the therapy can be administered. Afterwards, the stabilizing devices can be removed from the tympanic membrane and the tympanic membrane can heal, typically without the need for sutures.
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公开(公告)号：US11662561B2
公开(公告)日：2023-05-30
申请号：US17155800
申请日：2021-01-22
Applicant: Spiral Therapeutics Inc.
Inventor： Eugene de Juan , Signe Erickson , Charles Limb , Hugo Peris , Andrew Ayoob , Vrad Levering
IPC: G02B21/00 , G02B21/22 , A61B1/018 , A61B1/227 , A61B17/29 , A61M31/00 , A61B17/34 , A61M37/00 , A61B17/32 , A61B18/04 , A61B18/20 , A61F2/958 , A61B17/3205 , A61B18/14 , A61F11/20 , A61B17/00 , A61B18/00 , A61F2/18
CPC classification number: G02B21/0012 , A61B1/018 , A61B1/227 , A61B17/29 , A61B17/3205 , A61B17/320068 , A61B17/3423 , A61B17/3468 , A61B17/3478 , A61B18/04 , A61B18/1485 , A61B18/20 , A61F2/958 , A61F11/20 , A61F11/202 , A61M31/00 , A61M31/002 , A61M37/0015 , G02B21/0032 , G02B21/22 , A61B2017/00115 , A61B2017/00787 , A61B2017/00867 , A61B2017/32007 , A61B2018/00327 , A61B2217/005 , A61F2002/183 , A61F2250/0067 , A61M2037/0023 , A61M2037/0046 , A61M2205/04 , A61M2210/0662 , A61M2210/0668
Abstract: Systems and methods can be employed for trans-tympanic membrane access to the middle ear for delivery of a therapeutic agent, for example, to the round window niche adjacent to the cochlea under direct visualization. The systems and methods can also be used to improve accessibility and visualization for various otological surgical procedures, such as, but not limited to, cholesteatoma removal, tympanic membrane repair and ossicular chain repair.
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公开(公告)号：US20210231935A1
公开(公告)日：2021-07-29
申请号：US17155580
申请日：2021-01-22
Applicant: Spiral Therapeutics Inc.
Inventor： Eugene de Juan , Signe Erickson , Vrad Levering
Abstract: Devices, systems, and methods can be employed to facilitate indirect viewing into cavities such as, but not limited to, the middle ear space. Some embodiments have uses such as, but not limited to, facilitating visualization and procedures in the outer, middle, and/or inner ear in order to diagnose and/or treat disorders including, but not limited to, hearing loss and other ear disorders. In particular implementations, a surgical microscope is used in conjunction with an inverter lens and a distal lens. In some cases, the distal lens transverses a membrane or septum such as, but not limited to, the tympanic membrane. The distal lens can be an assembly combining two or more lenses, in some embodiments. For example, in some cases wide angle lenses, zoom lenses, lenses of other various shapes and/or prisms can be used in the distal lens.
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Patent Agency Ranking
公开(公告)号：US20210228237A1
公开(公告)日：2021-07-29
申请号：US17155800
申请日：2021-01-22
Applicant: Spiral Therapeutics Inc.
Inventor： Eugene de Juan , Signe Erickson , Charles Limb , Hugo Peris , Andrew Ayoob , Vrad Levering
IPC: A61B17/34
Abstract: Systems and methods can be employed for trans-tympanic membrane access to the middle ear for delivery of a therapeutic agent, for example, to the round window niche adjacent to the cochlea under direct visualization. The systems and methods can also be used to improve accessibility and visualization for various otological surgical procedures, such as, but not limited to, cholesteatoma removal, tympanic membrane repair and ossicular chain repair.
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公开(公告)号：US12164095B2
公开(公告)日：2024-12-10
申请号：US17155564
申请日：2021-01-22
Applicant: Spiral Therapeutics Inc.
Inventor： Eugene de Juan , Signe Erickson , Charles Limb , Hugo Peris , Nikhil Talreja , Andrew Ayoob
IPC: A61M31/00 , A61B1/018 , A61B1/227 , A61B17/29 , A61B17/32 , A61B17/3205 , A61B17/34 , A61B18/04 , A61B18/14 , A61B18/20 , A61F2/958 , A61F11/20 , A61M37/00 , G02B21/00 , G02B21/22 , A61B17/00 , A61B18/00 , A61F2/18
Abstract: Intra-tympanic injections of therapeutics into the inner ear can be used to treat conditions such as hearing loss. One or more stabilizing devices that define working channels can be temporarily implanted in the tympanic membrane. Purpose-built instruments such as endoscopes, forceps, and injections instruments can be passed through the working channels of the stabilizer devices to access the inner ear where the therapy can be administered. Afterwards, the stabilizing devices can be removed from the tympanic membrane and the tympanic membrane can heal, typically without the need for sutures.
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公开(公告)号：US20240019674A1
公开(公告)日：2024-01-18
申请号：US18369592
申请日：2023-09-18
Applicant: Spiral Therapeutics Inc.
Inventor： Eugene de Juan , Signe Erickson , Vrad Levering
IPC: G02B21/00 , G02B21/22 , A61B1/018 , A61B1/227 , A61B17/29 , A61M31/00 , A61B17/34 , A61M37/00 , A61B17/32 , A61B18/04 , A61B18/20 , A61F2/958 , A61B17/3205 , A61B18/14 , A61F11/20
CPC classification number: G02B21/0012 , G02B21/0032 , G02B21/22 , A61B1/018 , A61B1/227 , A61B17/29 , A61M31/002 , A61B17/3468 , A61B17/3478 , A61M37/0015 , A61B17/320068 , A61B17/3423 , A61B18/04 , A61B18/20 , A61F2/958 , A61M31/00 , A61B17/3205 , A61B18/1485 , A61F11/20 , A61F11/202 , A61M2205/04 , A61M2210/0662 , A61B2017/00115
Abstract: Devices, systems, and methods can be employed to facilitate indirect viewing into cavities such as, but not limited to, the middle ear space. Some embodiments have uses such as, but not limited to, facilitating visualization and procedures in the outer, middle, and/or inner ear in order to diagnose and/or treat disorders including, but not limited to, hearing loss and other ear disorders. In particular implementations, a surgical microscope is used in conjunction with an inverter lens and a distal lens. In some cases, the distal lens transverses a membrane or septum such as, but not limited to, the tympanic membrane. The distal lens can be an assembly combining two or more lenses, in some embodiments. For example, in some cases wide angle lenses, zoom lenses, lenses of other various shapes and/or prisms can be used in the distal lens.
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公开(公告)号：US20210228412A1
公开(公告)日：2021-07-29
申请号：US17155585
申请日：2021-01-22
Applicant: Spiral Therapeutics Inc.
Inventor： Eugene de Juan , Hugo Peris , Signe Erickson , Vrad Levering , Nikhil Talreja
Abstract: Devices, systems, and methods can be employed to facilitate performing procedures in the outer, middle, and/or inner ear in order to diagnose and/or treat disorders including, but not limited to, hearing loss and other ear disorders. For example, this document describes devices, systems and methods that include instruments and techniques to minimize the invasiveness and/or to enhance the efficacy of procedures that are performed in the outer, middle, and/or inner ear spaces such as mastoidectomy, tympanoplasty, cholesteatoma treatments, otosclerosis treatments, and Eustachian tube treatments.
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公开(公告)号：US20240398625A1
公开(公告)日：2024-12-05
申请号：US18696834
申请日：2022-09-27
Applicant: Spiral Therapeutics Inc.
Inventor： Signe Erickson , Vrad Levering , Eugene de Juan , Andrew Ayoob
Abstract: Devices, systems, and methods can be employed to facilitate therapeutic procedures in the inner ear in order to treat otic disorders including, but not limited to, hearing loss and other car disorders. In some examples, the systems and methods include instruments and techniques that can be used to minimize the invasiveness of procedures performed in the inner ear.
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