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1.Synthesis and novel salt forms of (R)-3-((E)-pyrrolidin-3-yl)vinyl)-5-tetrahydropyran-4-yloxy)pyridine 有权
标题翻译: (R)-3 - ((E) - 吡咯烷-3-基)乙烯基)-5-四氢吡喃-4-基氧基)吡啶的合成和新型盐形式公开(公告)号:US08633227B2
公开(公告)日:2014-01-21
申请号:US13125892
申请日:2009-11-30
申请人: Srinivasa Rao Akireddy , Scott R. Breining , Timothy J. Cuthbertson , Gary Maurice Dull , Gregory J. Gatto , John Genus , Philip S. Hammond , Joesph Pike Mitchener, Jr. , Julio A. Munoz , Pieter Albert Otten , Daniel Yohannes , Nikolai Fedorov
发明人: Srinivasa Rao Akireddy , Scott R. Breining , Timothy J. Cuthbertson , Gary Maurice Dull , Gregory J. Gatto , John Genus , Philip S. Hammond , Joesph Pike Mitchener, Jr. , Julio A. Munoz , Pieter Albert Otten , Daniel Yohannes , Nikolai Fedorov
IPC分类号: A61K31/4433 , C07D405/14
CPC分类号: A61K31/4439 , C07D405/14
摘要: The present invention relates to (R)-3-((E)-2-(pyrrolidin-3-yl)vinyl)-5-(tetrahydropyran-4-yloxy)pyridine, its salt forms, and to processes for the commercial-scale production of these compounds in sufficient purity and quality for use in pharmaceutical compositions.
摘要翻译: 本发明涉及(R)-3 - ((E)-2-(吡咯烷-3-基)乙烯基)-5-(四氢吡喃-4-基氧基)吡啶及其盐形式, 这些化合物的大规模生产具有足够的纯度和质量用于药物组合物。