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    Highly selective serotonin and norepinephrine dual reuptake inhibitor and use thereof
    5.
    发明申请
    Highly selective serotonin and norepinephrine dual reuptake inhibitor and use thereof 审中-公开
    高选择性5-羟色胺和去甲肾上腺素双重摄取抑制剂及其用途

    公开(公告)号：US20070015828A1

    公开(公告)日：2007-01-18

    申请号：US11485663

    申请日：2006-07-13

    申请人： Syed Shah ,  Eric Ehrnsperger ,  Richard Saunders ,  Mahdi Fawzi ,  Rocco Galante ,  Garth Whiteside

    发明人： Syed Shah ,  Eric Ehrnsperger ,  Richard Saunders ,  Mahdi Fawzi ,  Rocco Galante ,  Garth Whiteside

    IPC分类号： A61K31/277 ,  A61K31/137

    CPC分类号： C07C215/64 ,  C07B2200/13 ,  C07C217/52 ,  C07C2601/14

    摘要： Highly selective dual serotonin and norepinephrine reuptake inhibitors are provided. These compounds have a lower side-effect profile and are useful in compositions and products for use in treatment of a variety of conditions including depression, fibromyalgia, anxiety, panic disorder, agorophobia, post traumatic stress disorder, premenstrual dysphoric disorder, attention deficit disorder, obsessive compulsive disorder, social anxiety disorder, generalized anxiety disorder, autism, schizophrenia, obesity, anorexia nervosa, bulimia nervosa, Gilles de la Tourette Syndrome, vasomotor flushing, cocaine and alcohol addiction, sexual dysfunction, borderline personality disorder, fibromyalgia syndrome, diabetic neuropathic pain, chronic fatigue syndrome, pain, visceral pain, Shy Drager syndrome, Raynaud's syndrome, Parkinson's Disease, and epilepsy.

    摘要翻译： 提供了高选择性双重5-羟色胺和去甲肾上腺素再摄取抑制剂。 这些化合物具有较低的副作用特征，并且可用于治疗各种病症的组合物和产品，包括抑郁症，纤维肌痛，焦虑症，惊恐障碍，广泛性恐惧症，创伤后应激障碍，经前焦虑障碍，注意力缺陷障碍， 强迫症，社会焦虑症，广泛性焦虑症，自闭症，精神分裂症，肥胖症，神经性厌食症，神经性贪食症，杜氏综合征，血管舒缩性潮红，可卡因和酒精成瘾，性功能障碍，边缘性人格障碍，纤维肌痛综合征，糖尿病性神经病变 疼痛，慢性疲劳综合征，疼痛，内脏痛，Shie Drager综合征，雷诺综合征，帕金森病和癫痫。

    METHOD AND APPARATUS FOR DIRECT LASER CUTTING OF METAL STENTS
    7.
    发明申请
    METHOD AND APPARATUS FOR DIRECT LASER CUTTING OF METAL STENTS 审中-公开
    用于直接激光切割金属棒的方法和装置

    公开(公告)号：US20080021540A1

    公开(公告)日：2008-01-24

    申请号：US11830598

    申请日：2007-07-30

    申请人： Richard Saunders

    发明人： Richard Saunders

    IPC分类号： A61F2/06

    CPC分类号： A61F2/91 ,  A61F2/915 ,  A61F2002/91508 ,  A61F2002/91533 ,  A61F2230/0013 ,  B23K26/073 ,  B23K26/0823 ,  B23K26/142 ,  B23K26/1435 ,  B23K26/1436 ,  B23K26/1438 ,  B23K26/1462 ,  B23K26/1476 ,  B23K26/18 ,  B23K26/40 ,  B23K2103/05 ,  B23K2103/50 ,  G05B19/182 ,  G05B2219/45041 ,  G05B2219/45171 ,  Y10T29/49995 ,  Y10T29/49996

    摘要： An improved expandable stent for implantation in a body lumen, such as an artery, and an improved method for making it from a single length of tubing. The stent consists of a plurality of radially expandable cut cylindrical elements generally aligned on a common axis and interconnected by one or more interconnective elements, the elements having a rectangular cross-section from cut-to-cut. The individual radially expandable cylindrical elements are disposed in an undulating pattern. The stent is manufactured by direct laser cutting from a single metal tube using a finely focused laser beam passing through a coaxial gas jet structure to impinge on the working surface of the tube as the linear and rotary velocity of the tube is precisely controlled.

    摘要翻译： 用于植入体腔（例如动脉）中的改进的可扩张支架，以及用于使其从单一管道制成的改进方法。 支架由多个径向可膨胀的切割的圆柱形元件组成，其大体上在公共轴线上对齐并由一个或多个互连元件互连，所述元件具有从切割到切割的矩形横截面。 各个可径向扩张的圆柱形元件以波形图案设置。 通过使用精细聚焦的激光束通过同轴气体喷射结构从单个金属管直接激光切割来制造支架，以便精确地控制管的线性和旋转速度来冲击管的工作表面。

    Laser process to produce drug delivery channel in metal stents
    9.
    发明申请
    Laser process to produce drug delivery channel in metal stents 审中-公开
    激光工艺在金属支架中产生药物输送通道

    公开(公告)号：US20060054604A1

    公开(公告)日：2006-03-16

    申请号：US10939280

    申请日：2004-09-10

    申请人： Richard Saunders

    发明人： Richard Saunders

    IPC分类号： B23K26/38

    CPC分类号： B23K26/08 ,  A61F2/91 ,  B23K2101/06 ,  Y10T83/0341

    摘要： A method for forming a stent and for also forming channels in the outer surface of selected regions of the stent structure. The method includes impinging a laser beam generated by a diode pumped Q-switched pulsed Nd/YAG laser operating at the third harmonic on an outer surface of a stent and controllably machining channels in the outer surface of the stent. The depth of the channels may be controlled by adjusting the power and pulse rate of the laser, and also by adjusting the rate at which the stent moves relative to the laser beam.

    摘要翻译： 一种用于形成支架并且还在支架结构的选定区域的外表面中形成通道的方法。 该方法包括将由三次谐波操作的二极管泵浦Q开关脉冲Nd / YAG激光器产生的激光束照射在支架的外表面上并且可控地加工支架外表面中的通道。 可以通过调节激光的功率和脉冲速率以及通过调节支架相对于激光束移动的速率来控制通道的深度。

    Cervical orthosis
    10.
    发明申请
    Cervical orthosis 审中-公开
    宫颈矫形器

    公开(公告)号：US20050154339A1

    公开(公告)日：2005-07-14

    申请号：US10756004

    申请日：2004-01-13

    申请人： Daniel Farley ,  Anthony Mulac ,  Richard Saunders

    发明人： Daniel Farley ,  Anthony Mulac ,  Richard Saunders

    IPC分类号： A61F5/055 ,  A61F5/00

    CPC分类号： A61F5/055

    摘要： An external cervical fixation system includes a body configured to be secured to a patient, an attachment arm extending from the body, a bone screw, and a mounting fixture. The bone screw is mounted to the attachment arm, and has a threaded distal tip that is configured for threaded engagement with the patient's skull. The mounting fixture joins the attachment arm and the bone screw. The mounting fixture is configured to allow mounting and removal of the attachment arm and the bone screw when the bone screw is threadedly engaged with a patient's skull. The body can be adjusted independently of the bone screw.

    摘要翻译： 外部颈椎固定系统包括构造成固定到患者的主体，从身体延伸的附接臂，骨螺钉和安装夹具。 骨螺钉安装到附接臂上，并且具有被配置为与患者头骨螺纹接合的螺纹远端。 安装夹具连接连接臂和骨螺钉。 安装夹具被构造成当骨螺钉与患者的头骨螺纹接合时允许安装和移除附接臂和骨螺钉。 可以独立于骨螺钉调节身体。