-
公开(公告)号:US20100028261A1
公开(公告)日:2010-02-04
申请号:US12539936
申请日:2009-08-12
申请人: Stanislav EMELIANOV , Srivalleesha MALLIDI , Konstantin SOKOLOV , Timothy A. LARSON , Bo WANG , Evgeniya YANTSEN
发明人: Stanislav EMELIANOV , Srivalleesha MALLIDI , Konstantin SOKOLOV , Timothy A. LARSON , Bo WANG , Evgeniya YANTSEN
IPC分类号: A61K49/00 , G01N33/567 , G01N33/574 , C12Q1/68
CPC分类号: A61K49/225 , A61K49/00 , B82Y5/00
摘要: Methods relating to photoacoustic imaging of biological tissue are provided. One such method comprises contacting a biological tissue with a bioconjugate and irradiating the bioconjugate so as to generate an acoustic wave, wherein the bioconjugate comprises a nanoparticle and a moiety capable of selectively coupling a molecular marker. Suitable moieties include, among other things, epithelial growth factor receptor (EGFR).
摘要翻译: 提供了与生物组织的光声成像有关的方法。 一种这样的方法包括使生物组织与生物缀合物接触并照射生物缀合物以产生声波,其中生物缀合物包含纳米颗粒和能够选择性偶联分子标记的部分。 除了别的以外,合适的部分包括上皮生长因子受体(EGFR)。