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1.发明申请Positron emission tomography (PET) imager of excised tissue specimens for cancer margins definition 审中-公开用于癌边缘定义的切除组织标本的正电子发射断层扫描（PET）成像仪公开(公告)号：US20120101377A1
公开(公告)日：2012-04-26
申请号：US13317655
申请日：2011-10-25
IPC分类号： A61B6/00
CPC分类号： G01N33/57415 , A61B6/037 , G01N33/57434 , G01N33/60
摘要： A first embodiment can be a device comprising a means to define cancer margin definition of a tumor resection specimen via radiotracer uptake using a table top, mobile 3D PET imager in the operating room.
摘要翻译： 第一实施例可以是包括通过放射示踪器摄取来定义肿瘤切除标本的癌边缘定义的手段的装置，其使用桌面，手术室中的移动3D PET成像器。
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2.发明授权Method and apparatus for real time imaging and monitoring of radiotherapy beams 失效放射线束实时成像和监测的方法和装置公开(公告)号：US08049176B1
公开(公告)日：2011-11-01
申请号：US12316444
申请日：2008-12-12
IPC分类号： G01T1/16
CPC分类号： A61N5/1049 , A61N5/1071 , A61N2005/1052 , A61N2005/1054
摘要： A method and apparatus for real time imaging and monitoring of radiation therapy beams is designed to preferentially distinguish and image low energy radiation from high energy secondary radiation emitted from a target as the result of therapeutic beam deposition. A detector having low sensitivity to high energy photons combined with a collimator designed to dynamically image in the region of the therapeutic beam target is used.
摘要翻译： 用于实时成像和监测放射治疗光束的方法和装置被设计为优先区分和成像低能量辐射与作为治疗光束沉积的结果从目标发射的高能二次辐射。 使用与设计成在治疗束靶区域动态成像的准直仪结合的高能量光子的低灵敏度的检测器。
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3.发明申请Endorectal Prostate Probe Composed Of A Combined Mini Gamma Camera And Ultrasound Sensor 有权由联合迷你伽玛相机和超声波传感器组成的直肠前列腺探针公开(公告)号：US20140276032A1
公开(公告)日：2014-09-18
申请号：US13804606
申请日：2013-03-14
CPC分类号： A61B6/4417 , A61B5/4381 , A61B6/0407 , A61B6/4429 , A61B6/481 , A61B6/5247 , A61B6/54 , A61B8/12 , A61B8/4245 , A61B8/4254 , A61B8/4416 , A61B8/4444 , A61B8/5261 , A61B8/54 , A61B10/0241
摘要： A dual modality probe is disclosed having both a gamma probe sensor and an ultrasound sensor. A dual imaging system is provided having the probe and at least one external gamma imaging detector and a data acquisition computer system for collecting data simultaneously from the gamma probe sensor, the gamma imaging detector, and the ultrasound sensor of the probe. A method for evaluating a target organ of a patient utilizing the probe and imaging system, and performing a biopsy of the organ is disclosed.
摘要翻译： 公开了一种具有伽马探针传感器和超声波传感器的双模式探头。 提供了一种双成像系统，其具有探针和至少一个外部伽马成像检测器和用于从伽马探针传感器，伽马成像检测器和探头的超声波传感器同时收集数据的数据采集计算机系统。 公开了一种利用探针和成像系统评估患者的靶器官并进行器官的活组织检查的方法。
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4.发明授权Dedicated mobile high resolution prostate PET imager with an insertable transrectal probe 有权专用移动高分辨率前列腺PET成像仪与可插入的经直肠探针公开(公告)号：US07858944B2
公开(公告)日：2010-12-28
申请号：US12321666
申请日：2009-01-23
申请人： Stanislaw Majewski , James Proffitt
发明人： Stanislaw Majewski , James Proffitt
IPC分类号： G01T1/164
CPC分类号： G01T1/2985 , A61B6/037 , A61B6/425 , A61B6/4266 , A61B6/50 , A61B6/547 , G01T1/1603
摘要： A dedicated mobile PET imaging system to image the prostate and surrounding organs. The imaging system includes an outside high resolution PET imager placed close to the patient's torso and an insertable and compact transrectal probe that is placed in close proximity to the prostate and operates in conjunction with the outside imager. The two detector systems are spatially co-registered to each other. The outside imager is mounted on an open rotating gantry to provide torso-wide 3D images of the prostate and surrounding tissue and organs. The insertable probe provides closer imaging, high sensitivity, and very high resolution predominately 2D view of the prostate and immediate surroundings. The probe is operated in conjunction with the outside imager and a fast data acquisition system to provide very high resolution reconstruction of the prostate and surrounding tissue and organs.
摘要翻译： 专门的移动PET成像系统，用于对前列腺和周围器官进行成像。 成像系统包括放置在患者躯体附近的外部高分辨率PET成像器和放置在前列腺附近并与外部成像器结合操作的可插入和紧凑的经直肠探针。 两个检测器系统在空间上共同对齐。 外部成像仪安装在开放的旋转机架上，以提供前列腺和周围组织和器官的躯干宽的3D图像。 可插入的探针提供更接近的成像，高灵敏度和非常高的分辨率主要是前列腺和立即环境的2D视图。 探头与外部成像仪和快速数据采集系统一起运行，以提供前列腺和周围组织和器官的非常高分辨率的重建。
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5.发明授权High-resolution single photon planar and spect imaging of brain and neck employing a system of two co-registered opposed gamma imaging heads 失效脑和颈部的高分辨率单光子平面和光谱成像采用两个共同对照的γ成像头系统公开(公告)号：US08071949B2
公开(公告)日：2011-12-06
申请号：US12321667
申请日：2009-01-23
申请人： Stanislaw Majewski , James Proffitt
发明人： Stanislaw Majewski , James Proffitt
IPC分类号： G01T1/166
CPC分类号： G01T1/1641 , A61B6/037 , A61B6/4266 , A61B6/4417 , A61B6/501 , A61B6/583
摘要： A compact, mobile, dedicated SPECT brain imager that can be easily moved to the patient to provide in-situ imaging, especially when the patient cannot be moved to the Nuclear Medicine imaging center. As a result of the widespread availability of single photon labeled biomarkers, the SPECT brain imager can be used in many locations, including remote locations away from medical centers. The SPECT imager improves the detection of gamma emission from the patient's head and neck area with a large field of view. Two identical lightweight gamma imaging detector heads are mounted to a rotating gantry and precisely mechanically co-registered to each other at 180 degrees. A unique imaging algorithm combines the co-registered images from the detector heads and provides several SPECT tomographic reconstructions of the imaged object thereby improving the diagnostic quality especially in the case of imaging requiring higher spatial resolution and sensitivity at the same time.
摘要翻译： 一种紧凑，移动，专用的SPECT脑成像仪，可以轻松地移动到患者身上提供原位成像，特别是当患者无法移动到核医学成像中心时。 由于广泛使用单光子标记的生物标志物，SPECT脑成像仪可用于许多地点，包括远离医疗中心的偏远地区。 SPECT成像仪改善了患者头颈部区域的伽马射线的检测，具有较大的视野。 两个相同的轻量级伽马成像检测器头安装在旋转机架上，并以180度相互精确机械共同对准。 独特的成像算法结合了来自检测器头部的共同注册的图像，并提供了成像对象的多个SPECT断层摄影重建，从而提高了诊断质量，特别是在需要更高空间分辨率和灵敏度的成像的情况下。
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公开(公告)号：US20110089326A1
公开(公告)日：2011-04-21
申请号：US12319649
申请日：2009-01-09
申请人： Steven W. Falen , Richard A. Hoefer , Stanislaw Majewski , John Mckisson , Brian Kross , James Proffitt , Alexander Stolin , Andrew G. Weisenberger
发明人： Steven W. Falen , Richard A. Hoefer , Stanislaw Majewski , John Mckisson , Brian Kross , James Proffitt , Alexander Stolin , Andrew G. Weisenberger
IPC分类号： G01T1/166
CPC分类号： G01T1/2985 , A61B6/037 , G01N23/046 , G01N2223/419 , G01T1/1603
摘要： A mobile compact imaging system that combines both of the imaging system of and optical imaging into a single system which can be located in the operating room (OR) and provides faster feedback to determine if a tumor has been fully resected and if there are adequate surgical margins. While final confirmation is obtained from the pathology lab, such a device can reduce the total time necessary for the procedure and the number of iterations required to achieve satisfactory resection of a tumor with good margins.
摘要翻译： 一种移动式紧凑型成像系统，其将成像系统和光学成像系统结合到可以位于手术室（OR）中的单个系统中，并且提供更快的反馈以确定肿瘤是否已被完全切除，并且是否有足够的手术 利润率 虽然从病理实验室获得最终确认，但是这样的装置可以减少手术所需的总时间以及实现令人满意地切除具有良好边缘的肿瘤所需的迭代次数。
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公开(公告)号：US20100288935A1
公开(公告)日：2010-11-18
申请号：US12284285
申请日：2008-09-19
申请人： Stanislaw Majewski , James Proffitt
发明人： Stanislaw Majewski , James Proffitt
IPC分类号： A61B6/00
摘要： A brain imager includes a compact ring-like static PET imager mounted in a helmet-like structure. When attached to a patient's head, the helmet-like brain imager maintains the relative head-to-imager geometry fixed through the whole imaging procedure. The brain imaging helmet contains radiation sensors and minimal front-end electronics. A flexible mechanical suspension/harness system supports the weight of the helmet thereby allowing for patient to have limited movements of the head during imaging scans. The compact ring-like PET imager enables very high resolution imaging of neurological brain functions, cancer, and effects of trauma using a rather simple mobile scanner with limited space needs for use and storage.
摘要翻译： 大脑成像器包括安装在头盔状结构中的紧凑的环状静态PET成像器。 头盔般的大脑成像仪连接到患者的头部时，通过整个成像过程维持相对的头对头几何尺寸。 脑成像头盔包含辐射传感器和最小化的前端电子设备。 灵活的机械悬挂/线束系统支撑头盔的重量，从而允许患者在成像扫描期间具有头部的有限运动。 紧凑的环状PET成像仪可以使用相当简单的移动扫描仪对神经功能，癌症和创伤的影响进行非常高分辨率的成像，并且空间需求有限。
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8.发明申请公开(公告)号：US20100187424A1
公开(公告)日：2010-07-29
申请号：US12321666
申请日：2009-01-23
申请人： Stanislaw Majewski , James Proffitt
发明人： Stanislaw Majewski , James Proffitt
CPC分类号： G01T1/2985 , A61B6/037 , A61B6/425 , A61B6/4266 , A61B6/50 , A61B6/547 , G01T1/1603
摘要： A dedicated mobile PET imaging system to image the prostate and surrounding organs. The imaging system includes an outside high resolution PET imager placed close to the patient's torso and an insertable and compact transrectal probe that is placed in close proximity to the prostate and operates in conjunction with the outside imager. The two detector systems are spatially co-registered to each other. The outside imager is mounted on an open rotating gantry to provide torso-wide 3D images of the prostate and surrounding tissue and organs. The insertable probe provides closer imaging, high sensitivity, and very high resolution predominately 2D view of the prostate and immediate surroundings. The probe is operated in conjunction with the outside imager and a fast data acquisition system to provide very high resolution reconstruction of the prostate and surrounding tissue and organs.
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9.发明申请Apparatus and Implementation Method of a Set of Universal Compact Portable MR-Compatible PET Inserts to Convert Whole-Body MRI Scanners Into Organ-Specific Hybrid PET/MRI Imagers 审中-公开一套通用紧凑便携式MR兼容PET插件将全身MRI扫描仪转换为器官特异性混合型PET / MRI成像仪的设备和实现方法公开(公告)号：US20140275965A1
公开(公告)日：2014-09-18
申请号：US13827557
申请日：2013-03-14
IPC分类号： G01R33/48
CPC分类号： G01R33/481 , G01T1/1603 , G01T1/2985
摘要： A Positron Emission Tomography (PET″) insert for use with a Magnetic Resonance Imaging (“MRI”) scanning device, the PET insert including a plurality of photodetector modules provided adjacent each other in an array, the plurality of photodetector modules configured for placement adjacent a body of a patient and sized to be received in a magnetic bore of the MRI scanning device with the patient, the photodetector modules providing detection of gamma annihilation photons, and a Radio Frequency (“RF”) coil provided between the patient and the plurality of photodetector modules. Each of the plurality of photodetector modules includes a pixelated scintillator array provided for alignment adjacent the patient's body, and a shielding block including silicon photomultiplier pads and passive electronic circuitry only.
摘要翻译： 用于与磁共振成像（“MRI”）扫描装置一起使用的正电子发射断层扫描（PET“）插入物，所述PET插入物包括以阵列相邻设置的多个光电检测器模块，所述多个光电检测器模块被配置为邻近放置 患者的身体，并且被设计成被容纳在患者的MRI扫描装置的磁性孔中，所述光检测器模块提供伽马湮灭光子的检测，以及设置在患者与多个之间的射频（“RF”）线圈 的光电检测器模块。 多个光检测器模块中的每一个包括用于与患者身体相邻的对准的像素化闪烁体阵列，以及仅包括硅光电倍增管和无源电子电路的屏蔽块。
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公开(公告)号：US07884331B2
公开(公告)日：2011-02-08
申请号：US12284285
申请日：2008-09-19
申请人： Stanislaw Majewski , James Proffitt
发明人： Stanislaw Majewski , James Proffitt
IPC分类号： G01T1/161
摘要： A brain imager includes a compact ring-like static PET imager mounted in a helmet-like structure. When attached to a patient's head, the helmet-like brain imager maintains the relative head-to-imager geometry fixed through the whole imaging procedure. The brain imaging helmet contains radiation sensors and minimal front-end electronics. A flexible mechanical suspension/harness system supports the weight of the helmet thereby allowing for patient to have limited movements of the head during imaging scans. The compact ring-like PET imager enables very high resolution imaging of neurological brain functions, cancer, and effects of trauma using a rather simple mobile scanner with limited space needs for use and storage.
摘要翻译： 大脑成像器包括安装在头盔状结构中的紧凑的环状静态PET成像器。 头盔般的大脑成像仪连接到患者的头部时，通过整个成像过程维持相对的头对头几何尺寸。 脑成像头盔包含辐射传感器和最小化的前端电子设备。 灵活的机械悬挂/线束系统支撑头盔的重量，从而允许患者在成像扫描期间具有头部的有限运动。 紧凑的环状PET成像仪可以使用相当简单的移动扫描仪对神经功能，癌症和创伤的影响进行非常高分辨率的成像，并且空间需求有限。
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