公开(公告)号：US20070197485A1

公开(公告)日：2007-08-23

申请号：US11627183

申请日：2007-01-25

申请人： Stefan Anker ,  Andrew Coats ,  Hans-Dieter Volk ,  Ralf Schuman ,  Mathias Plauth ,  Herbert Lochs

发明人： Stefan Anker ,  Andrew Coats ,  Hans-Dieter Volk ,  Ralf Schuman ,  Mathias Plauth ,  Herbert Lochs

IPC分类号： A61K31/56

CPC分类号： A61K31/575

摘要： A method for treating cachecia, liver disease, and other wasting syndromes is provided. The treatment method comprises administering a therapeutically effective amount of a compound that is able to reduce the production, absorption and/or the effect of an endotoxin. Examples of such compounds include, but are not limited to, bile acids; bactericidal/permeability increasing proteins; lipoproteins; antibodies capable of binding to endotoxins; LPS binding protein; activated charcoal, Fuller's earth, attapulgite, kaolin or bentonite or a clay; a drug blocking effectively signaling through toll-like receptors; and calostrum or human, bovine or other mammals.

摘要翻译： 提供了一种治疗缓解期，肝病和其他消瘦综合征的方法。 治疗方法包括施用治疗有效量的能够降低内毒素的产生，吸收和/或作用的化合物。 这些化合物的实例包括但不限于胆汁酸; 杀菌/渗透性增加蛋白质; 脂蛋白; 能够结合内毒素的抗体; LPS结合蛋白; 活性炭，富勒土，绿坡缕石，高岭土或膨润土或粘土; 药物阻断通过收费样受体有效发信号; 和饮水或人，牛或其他哺乳动物。