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公开(公告)号:US20110033502A1
公开(公告)日:2011-02-10
申请号:US12116159
申请日:2008-05-06
申请人: Stefan H.I. Kappe , Kai-Uwe C. Matuschewski , Ann-Kristin Mueller , Kelley van Buskirk , Mehdi Labaied , Ahmed Sayed Ibrahim Aly , Alan Frederick Cowman , Alexander Gerd Maier
发明人: Stefan H.I. Kappe , Kai-Uwe C. Matuschewski , Ann-Kristin Mueller , Kelley van Buskirk , Mehdi Labaied , Ahmed Sayed Ibrahim Aly , Alan Frederick Cowman , Alexander Gerd Maier
IPC分类号: A61K39/015 , A61P33/06 , C12N1/10
CPC分类号: C12N1/36 , A61K39/015 , A61K2039/522 , Y02A50/412
摘要: Method for inoculating a vertebrate host against malaria, by administering to the host a live Plasmodium organism that is genetically engineered to disrupt a liver-stage-specific gene function.
摘要翻译: 通过向宿主施用遗传工程改造以破坏肝阶段特异性基因功能的活疟原虫生物体接种脊椎动物宿主免受疟疾的方法。
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公开(公告)号:US08168166B2
公开(公告)日:2012-05-01
申请号:US12116159
申请日:2008-05-06
申请人: Stefan H. I. Kappe , Kai-Uwe C. Matuschewski , Ann-Kristin Mueller , Kelley van Buskirk , Mehdi Labaied , Ahmed Sayed Ibrahim Aly , Alan Frederick Cowman , Alexander Gerd Maier
发明人: Stefan H. I. Kappe , Kai-Uwe C. Matuschewski , Ann-Kristin Mueller , Kelley van Buskirk , Mehdi Labaied , Ahmed Sayed Ibrahim Aly , Alan Frederick Cowman , Alexander Gerd Maier
CPC分类号: C12N1/36 , A61K39/015 , A61K2039/522 , Y02A50/412
摘要: Method for inoculating a vertebrate host against malaria, by administering to the host a live Plasmodium organism that is genetically engineered to disrupt a liver-stage-specific gene function.
摘要翻译: 通过向宿主施用遗传工程改造以破坏肝阶段特异性基因功能的活疟原虫生物体接种脊椎动物宿主免受疟疾的方法。
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