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1.
公开(公告)号:US08173429B2
公开(公告)日:2012-05-08
申请号:US12689513
申请日:2010-01-19
申请人: Stefan Pellenz , Bernard Dujon , Alexis Harington , John Sullivan Harington, legal representative , Eoné de Wet, legal representative , Bernd Schafer
发明人: Stefan Pellenz , Bernard Dujon , Alexis Harington , Bernd Schafer
CPC分类号: C12N15/907 , A01K2217/05 , C12N9/22
摘要: Isolated DNAs encoding the enzyme I-SpomI and its recognition and cutting site are provided. The DNA sequences can be incorporated in cloning and expression vectors, transformed cell lines and transgenic animals. The vectors are useful in gene mapping and site-directed insertion of genes.
摘要翻译: 提供了编码酶I-SpomI及其识别和切割位点的分离的DNA。 DNA序列可以并入克隆和表达载体,转化细胞系和转基因动物中。 载体可用于基因作图和基因定点插入。
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2.
公开(公告)号:US07732194B2
公开(公告)日:2010-06-08
申请号:US11250633
申请日:2005-10-17
申请人: Stefan Pellenz , Bernard Dujon , Alexis Harington , John Sullivan Harington, legal representative , Eoné de Wet, legal representative , Bernd Schafer
发明人: Stefan Pellenz , Bernard Dujon , Alexis Harington , Bernd Schafer
CPC分类号: C12N15/907 , A01K2217/05 , C12N9/22
摘要: Isolated DNAs encoding the enzyme I-SpomI and its recognition and cutting site are provided. The DNA sequences can be incorporated in cloning and expression vectors, transformed cell lines and transgenic animals. The vectors are useful in gene mapping and site-directed insertion of genes.
摘要翻译: 提供了编码酶I-SpomI及其识别和切割位点的分离的DNA。 DNA序列可以并入克隆和表达载体,转化细胞系和转基因动物中。 载体可用于基因作图和基因定点插入。
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公开(公告)号:US20060286656A1
公开(公告)日:2006-12-21
申请号:US11250633
申请日:2005-10-17
申请人: Stefan Pellenz , Bernard Dujon , Alexis Harington , JS Harington , Bernd Schafer
发明人: Stefan Pellenz , Bernard Dujon , Alexis Harington , JS Harington , Bernd Schafer
IPC分类号: C12Q1/68 , A01K67/033 , C07H21/02 , C12P21/06 , C12N9/22 , C12N1/21 , C12N1/18 , C12N5/06 , C12N15/861
CPC分类号: C12N15/907 , A01K2217/05 , C12N9/22
摘要: Isolated DNAs encoding the enzyme I-SpomI and its recognition and cutting site are provided. The DNA sequences can be incorporated in cloning and expression vectors, transformed cell lines and transgenic animals. The vectors are useful in gene mapping and site-directed insertion of genes.
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公开(公告)号:US20100229253A1
公开(公告)日:2010-09-09
申请号:US12689513
申请日:2010-01-19
申请人: Stefan Pellenz , Bernard Dujon , Alexis Harington , Bernd Schafer
发明人: Stefan Pellenz , Bernard Dujon , Alexis Harington , Bernd Schafer
IPC分类号: C12N15/87 , C07H21/04 , C12N15/63 , C12N5/10 , C12N1/15 , C12N1/19 , C12N1/21 , A01K67/027 , A01H5/00 , C12N15/82 , C12N15/74 , C12N9/16
CPC分类号: C12N15/907 , A01K2217/05 , C12N9/22
摘要: Isolated DNAs encoding the enzyme I-Spoml and its recognition and cutting site are provided. The DNA sequences can be incorporated in cloning and expression vectors, transformed cell lines and transgenic animals. The vectors are useful in gene mapping and site-directed insertion of genes.
摘要翻译: 提供了编码酶I-Spom1及其识别和切割位点的分离的DNA。 DNA序列可以并入克隆和表达载体,转化细胞系和转基因动物中。 载体可用于基因作图和基因定点插入。
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5.
公开(公告)号:US20060183129A1
公开(公告)日:2006-08-17
申请号:US10933476
申请日:2004-09-03
申请人: Stefan Pellenz , Bernard Dujon , Alexis Harington , Bernd Schafer
发明人: Stefan Pellenz , Bernard Dujon , Alexis Harington , Bernd Schafer
CPC分类号: C12N15/907 , A01K2217/05 , C12N9/22
摘要: Isolated DNAs encoding the enzyme I-SpomI and its recognition and cutting site are provided. The DNA sequences can be incorporated in cloning and expression vectors, transformed cell lines and transgenic animals. The vectors are useful in gene mapping and site-directed insertion of genes.
摘要翻译: 提供了编码酶I-SpomI及其识别和切割位点的分离的DNA。 DNA序列可以并入克隆和表达载体,转化细胞系和转基因动物中。 载体可用于基因作图和基因定点插入。
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公开(公告)号:US20060142766A1
公开(公告)日:2006-06-29
申请号:US10527339
申请日:2003-09-11
申请人: Bernd Schafer
发明人: Bernd Schafer
IPC分类号: A61F2/30
CPC分类号: A61B17/8605 , A61B17/7059 , A61B17/8052 , A61B2017/8655
摘要: The invention relates to a cervical vertebra plate (10) for osteosynthesis, having two receiving openings for the screw heads (18) of bone screws (16) in order to secure the cervical vertebra plate to two cervical vertebrae. The receiving openings have grooves (22) in the distal region on the periphery thereof and the depth of the grooves increases from a proximal to a distal end. The invention also relates to a bone screw (18) comprising a screw head (16) and a screw shank. The screw head comprises grooves (34) on the outer periphery thereof and the depth of the grooves varies along the length thereof.
摘要翻译: 本发明涉及一种用于骨接合术的颈椎板(10),其具有两个用于骨螺钉(16)的螺钉头(18)的接收开口,以将颈椎板固定到两个颈椎上。 接收开口在其周边的远侧区域中具有凹槽(22),并且凹槽的深度从近端到远端增加。 本发明还涉及一种包括螺钉头(16)和螺钉柄的骨螺钉(18)。 螺钉头在其外周上包括凹槽(34),并且凹槽的深度沿其长度变化。
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公开(公告)号:US6117137A
公开(公告)日:2000-09-12
申请号:US299621
申请日:1999-04-27
申请人: Henry Halm , Bernd Schafer
发明人: Henry Halm , Bernd Schafer
CPC分类号: A61B17/7032 , A61B17/7005
摘要: The present invention relates to an osteosynthesis device with a bone screw and a correction rod, in which the correction rod is placed in a bifurcated head of the bone screw and axially fixed. To that end, the bifurcated head has structure that prevent the longitudinal displacement of the correction rod.
摘要翻译: 本发明涉及具有骨螺钉和矫正杆的骨接合装置,其中将矫正杆放置在骨螺钉的分叉头部并且轴向固定。 为此,分叉头具有防止校正杆的纵向位移的结构。
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公开(公告)号:US5643261A
公开(公告)日:1997-07-01
申请号:US400252
申请日:1995-03-08
申请人: Bernd Schafer , Klaus Zielke
发明人: Bernd Schafer , Klaus Zielke
IPC分类号: A61B17/70
CPC分类号: A61B17/7008 , A61B17/7044 , A61B17/701 , A61B17/7032
摘要: In an osteosynthesis device, a bone plate is secured to a bone with at least two bone screws and the bone screws serve to bear and receive two rods, via which the correction and stabilization of the bones takes place.
摘要翻译: 在骨接合装置中,用至少两个骨螺钉将骨板固定到骨头上,并且骨螺钉用于承受和接收两个杆,骨骼发生矫正和稳定。
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公开(公告)号:US07229442B2
公开(公告)日:2007-06-12
申请号:US10527339
申请日:2003-09-11
申请人: Bernd Schafer
发明人: Bernd Schafer
IPC分类号: A61B17/56
CPC分类号: A61B17/8605 , A61B17/7059 , A61B17/8052 , A61B2017/8655
摘要: The invention relates to a cervical vertebra plate (10) for osteosynthesis, having two receiving openings for the screw heads (18) of bone screws (16) in order to secure the cervical vertebra plate to two cervical vertebrae. The receiving openings have grooves (22) in the distal region on the periphery thereof and the depth of the grooves increases from a proximal to a distal end. The invention also relates to a bone screw (18) comprising a screw head (16) and a screw shank. The screw head comprises grooves (34) on the outer periphery thereof and the depth of the grooves varies along the length thereof.
摘要翻译: 本发明涉及一种用于骨接合术的颈椎板(10),其具有两个用于骨螺钉(16)的螺钉头(18)的接收开口,以将颈椎板固定到两个颈椎上。 接收开口在其周边的远侧区域中具有凹槽(22),并且凹槽的深度从近端到远端增加。 本发明还涉及一种包括螺钉头(16)和螺钉柄的骨螺钉(18)。 螺钉头在其外周上包括凹槽(34),并且凹槽的深度沿其长度变化。
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公开(公告)号:US5713898A
公开(公告)日:1998-02-03
申请号:US545575
申请日:1996-01-29
申请人: Ralf Stucker , Gunther Rehder , Bernd Schafer
发明人: Ralf Stucker , Gunther Rehder , Bernd Schafer
CPC分类号: A61B17/7044 , A61B17/7032 , A61B17/7043
摘要: In an orthopedic surgical holding device for a correcting rod, having a bone plate which can be fastened on the bone, a receiver device for the correcting rod and a fixing device maintaining the correcting rod in the receiver device. An optimal transfer of the occurring forces and moments is achieved in that the bone plate can be fixed independently of the receiver device (10) and has a bearing for the receiver device, and in that the receiver device can be pushed into the bearing from the proximal side and in the course of this extends through the bone plate and extends beyond it on the distal side for receiving the correcting rod.
摘要翻译: PCT No.PCT / EP94 / 01606 Sec。 371日期1996年1月29日 102(e)日期1996年1月29日PCT 1994年5月18日PCT PCT。 公开号WO94 / 26194 PCT 日期:1994年11月24日在矫正杆用矫形外科手术保持装置中,具有可以固定在骨头上的骨板,用于矫正杆的接收装置和将矫正杆保持在接收装置中的固定装置。 实现发生的力和力矩的最佳转移是因为骨板可以独立于接收器装置(10)固定,并且具有用于接收装置的轴承,并且接收装置可从 近端侧并且在其过程中延伸穿过骨板并在远侧延伸超过它以接收校正杆。
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