公开(公告)号：US06294523B1

公开(公告)日：2001-09-25

申请号：US09272755

申请日：1999-03-22

申请人： Steven B. Levery ,  Sen-itiroh Hakomori ,  Mark R Stroud

发明人： Steven B. Levery ,  Sen-itiroh Hakomori ,  Mark R Stroud

IPC分类号： A61K31715

CPC分类号： A61K31/715 ,  C07K2317/732 ,  C07K2317/734 ,  C08B37/006

摘要： A variety of compounds are provided which are useful as immunogens and as tumor markers. The present invention discloses methods relating to the detection of cancer. Extended forms of the lacto-series type 1 chain are shown to be present in various cancer tissues. The present invention also provides a cell line and the monoclonal antibody produced therefrom. Such an antibody has a number of uses, including in diagnostic or therapeutic methods.

摘要翻译： 提供了可用作免疫原和肿瘤标记物的各种化合物。 本发明公开了与癌症的检测有关的方法。 乳糖系列1型链的延伸形式显示存在于各种癌组织中。 本发明还提供了由其制备的细胞系和单克隆抗体。 这样的抗体具有许多用途，包括诊断或治疗方法。