公开(公告)号：US07229966B2

公开(公告)日：2007-06-12

申请号：US10780325

申请日：2004-02-17

申请人： Steven C. Quay ,  Gordon Brandt ,  Mary S. Kleppe ,  Conor J. MacEvilly

发明人： Steven C. Quay ,  Gordon Brandt ,  Mary S. Kleppe ,  Conor J. MacEvilly

IPC分类号： A61K38/17 ,  A61K38/28 ,  C07K14/435 ,  B05B11/02

CPC分类号： A61K9/0043 ,  A61K31/045 ,  A61K31/70 ,  A61K31/7012 ,  A61K31/715 ,  A61K31/724 ,  A61K38/22

摘要： Pharmaceutical compositions and methods are described comprising at least one Y2 receptor-binding peptide, such as peptide YY(PYY), Neuropeptide Y (NPY) or Pancreatic Peptide (PP) and one or more mucosal delivery-enhancing agents for enhanced nasal mucosal delivery of the peptide YY, for treating a variety of diseases and conditions in mammalian subjects, including obesity.

公开(公告)号：US07186691B2

公开(公告)日：2007-03-06

申请号：US10745069

申请日：2003-12-23

申请人： Steven C. Quay ,  Gordon Brandt ,  Mary S. Kleppe ,  Conor J. MacEvilly

发明人： Steven C. Quay ,  Gordon Brandt ,  Mary S. Kleppe ,  Conor J. MacEvilly

IPC分类号： A61K38/17 ,  A61K38/28 ,  C07K14/435

CPC分类号： A61K9/08 ,  A61K9/0043 ,  A61K31/724 ,  A61K38/22 ,  A61K38/2271 ,  A61K45/06 ,  A61K47/24 ,  A61K47/26 ,  A61K47/40 ,  A61K2300/00

摘要： Pharmaceutical compositions and methods are described comprising at least one Y2 receptor-binding peptide, such as peptide YY(PYY), Neuropeptide Y (NPY) or Pancreatic Peptide (PP) and one or more mucosal delivery-enhancing agents for enhanced nasal mucosal delivery of the peptide YY, for treating a variety of diseases and conditions in mammalian subjects, including obesity.

公开(公告)号：US07157426B2

公开(公告)日：2007-01-02

申请号：US10768288

申请日：2004-01-30

申请人： Steven C. Quay ,  Gordon Brandt ,  Mary S. Kleppe ,  Conor J. MacEvilly

发明人： Steven C. Quay ,  Gordon Brandt ,  Mary S. Kleppe ,  Conor J. MacEvilly

IPC分类号： A61K38/17 ,  A61K9/10 ,  A61K38/22 ,  A61L9/14 ,  C07K14/435

CPC分类号： A61K9/08 ,  A61K9/0043 ,  A61K31/724 ,  A61K38/22 ,  A61K38/2271 ,  A61K45/06 ,  A61K47/24 ,  A61K47/26 ,  A61K47/40 ,  A61K2300/00

摘要： Pharmaceutical compositions and methods are described comprising at least one Y2 receptor-binding peptide, such as peptide YY(PYY), Neuropeptide Y (NPY) or Pancreatic Peptide (PP) and one or more mucosal delivery-enhancing agents for enhanced nasal mucosal delivery of the peptide YY, for treating a variety of diseases and conditions in mammalian subjects, including obesity.

摘要翻译： 描述了药物组合物和方法，其包含至少一种Y2受体结合肽，例如肽YY（PYY），神经肽Y（NPY）或胰腺肽（PP）和一种或多种用于增强鼻粘膜递送的粘膜递送增强剂 肽YY，用于治疗哺乳动物受试者中的各种疾病和病症，包括肥胖症。