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    Implantable heart assist system and method of applying same
    3.
    发明授权
    Implantable heart assist system and method of applying same 有权
    植入式心脏辅助系统及其应用方法

    公开(公告)号：US07331921B2

    公开(公告)日：2008-02-19

    申请号：US10878592

    申请日：2004-06-28

    申请人： Anthony Viole ,  Laksen Sirimanne ,  Steven F. Bolling ,  Shawn O'Leary ,  Robert Pecor ,  Ryan Kelly ,  Wolfgang Werner ,  Masoud Beizai

    发明人： Anthony Viole ,  Laksen Sirimanne ,  Steven F. Bolling ,  Shawn O'Leary ,  Robert Pecor ,  Ryan Kelly ,  Wolfgang Werner ,  Masoud Beizai

    IPC分类号： A61M1/12

    CPC分类号： A61M1/3621 ,  A61M1/10 ,  A61M1/1005 ,  A61M1/1008 ,  A61M1/101 ,  A61M1/1034 ,  A61M1/107 ,  A61M1/1086 ,  A61M1/122 ,  A61M1/125 ,  A61M1/3655 ,  A61M25/0026 ,  A61M25/007

    摘要： An extracardiac pumping for supplementing the circulation of blood, including the cardiac output, in a patient without any component thereof being connected to the patient's heart, and methods of using same. One embodiment of the intravascular extracardiac system comprises a pump with inflow and outflow conduits that are sized and configured to be implantable intravascularly through a non-primary vessel, whereby it may positioned where desired within the patient's vasculature. The system comprises a subcardiac pump that may be driven directly or electromagnetically from within or without the patient. The pump is configured to be operated continuously or in a pulsatile fashion, synchronous with the patient's heart, thereby potentially reducing the afterload of the heart. In another embodiment, the system is positioned extracorporeally, with the inflow conduit and outflow conduit applied percutaneously to a non-primary vessel for circulating blood to and from the non-primary vessel or between the non-primary vessel and another blood vessel within the patient's vasculature.

    摘要翻译： 用于补充患者的血液循环（包括心输出量）的心外泵送，而不将其任何组分连接到患者的心脏，以及使用它们的方法。 血管内心外系统的一个实施例包括具有流入和流出导管的泵，其尺寸和构造可通过非主血管血管内植入，由此可将其定位在患者的脉管系统内所需的位置。 该系统包括可以从患者内部或不具有直接驱动或电磁驱动的亚心脏泵。 泵被配置为与患者的心脏同步地连续地或以脉动方式操作，从而潜在地减少心脏的后负荷。 在另一个实施例中，系统被定位在体外，流入管道和流出管道经皮施加到非主血管，用于使血液循环到非主血管或非主血管之间或非主血管与患者的另一血管之间循环 脉管系统

    Implantable heart assist system and method of applying same
    5.
    发明授权
    Implantable heart assist system and method of applying same 有权
    植入式心脏辅助系统及其应用方法

    公开(公告)号：US07458929B2

    公开(公告)日：2008-12-02

    申请号：US11121352

    申请日：2005-05-03

    申请人： Steven F. Bolling ,  Anthony Viole ,  Shawn O'Leary

    发明人： Steven F. Bolling ,  Anthony Viole ,  Shawn O'Leary

    IPC分类号： A61M1/12

    CPC分类号： A61M1/101 ,  A61M1/10 ,  A61M1/1005 ,  A61M1/1008 ,  A61M1/1034 ,  A61M1/107 ,  A61M1/1086 ,  A61M1/12 ,  A61M1/122 ,  A61M1/125 ,  A61M1/3621 ,  A61M1/3653 ,  A61M1/3655 ,  A61M1/3659 ,  A61M25/0026 ,  A61M25/003 ,  A61M25/007 ,  A61M2230/04

    摘要： An extracardiac pumping for supplementing the circulation of blood, including the cardiac output, in a patient without any component thereof being connected to the patient's heart, and methods of using same. One embodiment provides a vascular graft that has a first end that is sized and configured to couple to a non-primary blood vessel and a second end that is fluidly coupled to a pump to conduct blood between the pump and the non-primary blood vessel. An outflow conduit is also provided that has a first end sized and configured to be positioned within the same or different blood vessel, whether primary or non-primary, through the vascular graft. The outflow conduit is fluidly coupled to the pump to conduct blood between the pump and the patient. The vascular graft may be connected to the blood vessel subcutaneously to permit application of the extracardiac pumping system in a minimally-invasive procedure.

    摘要翻译： 用于补充患者的血液循环（包括心输出量）的心外泵送，而不将其任何组分连接到患者的心脏，以及使用它们的方法。 一个实施例提供一种血管移植物，其具有第一端的尺寸和构造以耦合到非原发性血管和流体耦合到泵的第二端，以在泵和非原发性血管之间引导血液。 还提供了流出管道，其具有第一端的尺寸和构造以通过血管移植物定位在相同或不同的血管内，无论是初级的还是非原发的。 流出管道流体耦合到泵以在泵和患者之间进行血液。 血管移植物可以皮下连接到血管，以允许将心脏内泵送系统应用于微创手术。

    Implantable heart assist system and method of applying same
    6.
    发明授权
    Implantable heart assist system and method of applying same 失效
    植入式心脏辅助系统及其应用方法

    公开(公告)号：US06889082B2

    公开(公告)日：2005-05-03

    申请号：US10289467

    申请日：2002-11-06

    申请人： Steven F. Bolling ,  Anthony Viole ,  Shawn O'Leary

    发明人： Steven F. Bolling ,  Anthony Viole ,  Shawn O'Leary

    IPC分类号： A61M1/10 ,  A61M1/12 ,  A61M1/36 ,  A61M25/00 ,  A61M39/10

    CPC分类号： A61M1/101 ,  A61M1/10 ,  A61M1/1005 ,  A61M1/1008 ,  A61M1/1034 ,  A61M1/107 ,  A61M1/1086 ,  A61M1/12 ,  A61M1/122 ,  A61M1/125 ,  A61M1/3621 ,  A61M1/3653 ,  A61M1/3655 ,  A61M1/3659 ,  A61M25/0026 ,  A61M25/003 ,  A61M25/007 ,  A61M2230/04

    摘要： An extracardiac pumping for supplementing the circulation of blood, including the cardiac output, in a patient without any component thereof being connected to the patient's heart, and methods of using same. One embodiment provides a vascular graft that has a first end that is sized and configured to couple to a non-primary blood vessel and a second end that is fluidly coupled to a pump to conduct blood between the pump and the non-primary blood vessel. An outflow conduit is also provided that has a first end sized and configured to be positioned within the same or different blood vessel, whether primary or non-primary, through the vascular graft. The outflow conduit is fluidly coupled to the pump to conduct blood between the pump and the patient. The vascular graft may be connected to the blood vessel subcutaneously to permit application of the extracardiac pumping system in a minimally-invasive procedure.

    摘要翻译： 用于补充患者的血液循环（包括心输出量）的心外泵送，而不将其任何组分连接到患者的心脏，以及使用它们的方法。 一个实施例提供一种血管移植物，其具有第一端的尺寸和构造以耦合到非原发性血管和流体耦合到泵以在泵和非原发性血管之间进行血液的第二端。 还提供了流出管道，其具有第一端的尺寸和构造以通过血管移植物定位在相同或不同的血管内，无论是初级的还是非原发的。 流出管道流体耦合到泵以在泵和患者之间进行血液。 血管移植物可以皮下连接到血管，以允许将心脏内泵送系统应用于微创手术。

    Implantable heart assist system and method of applying same
    10.
    发明授权
    Implantable heart assist system and method of applying same 有权
    植入式心脏辅助系统及其应用方法

    公开(公告)号：US06390969B1

    公开(公告)日：2002-05-21

    申请号：US09552979

    申请日：2000-04-21

    申请人： Steven F. Bolling ,  Morteza Gharib ,  Gabriel Aldea ,  Mary Lynn Gaddis ,  Anthony Viole

    发明人： Steven F. Bolling ,  Morteza Gharib ,  Gabriel Aldea ,  Mary Lynn Gaddis ,  Anthony Viole

    IPC分类号： A61M110

    CPC分类号： A61M1/3621 ,  A61M1/10 ,  A61M1/1008 ,  A61M1/101 ,  A61M1/107 ,  A61M1/122 ,  A61M1/127 ,  A61M1/3655 ,  A61M25/0026 ,  A61M25/007

    摘要： An extracardiac pumping for supplementing the circulation of blood, including the cardiac output, in a patient without any component thereof being connected to the patient's heart, and method of using same. One embodiment of the extracardiac system comprises an implantable or portable subcardiac pump, whereby the pump draws blood through an inflow conduit fluidly coupled to a non-primary artery via a cannula and discharges blood through an outflow conduit fluidly coupled to a second non-primary artery via a cannula, wherein at least one of the cannulas projects well into the patient's vascular system. The pump may be operated continuously or in a pulsatile fashion, synchronous with the patient's heart, thereby potentially reducing the afterload of the heart.

    摘要翻译： 用于补充患者的血液循环（包括心输出量）的心外泵送，而不将其任何组分连接到患者的心脏，以及使用它们的方法。 心脏外系统的一个实施例包括可植入或便携式的心脏心脏泵，其中泵通过经由套管流体耦合到非主动脉的流入管吸取血液，并通过与第二非主动脉流体耦合的流出导管排出血液 通过套管，其中至少一个插管伸入病人的血管系统中。 泵可以连续地或以脉动方式操作，与患者的心脏同步，从而潜在地减少心脏的后负荷。