公开(公告)号：US06313147B1

公开(公告)日：2001-11-06

申请号：US09520736

申请日：2000-03-08

申请人： Steven Howard Shaber ,  Lixin Zhang ,  Edward Michael Szapacs ,  James Allen Quinn

发明人： Steven Howard Shaber ,  Lixin Zhang ,  Edward Michael Szapacs ,  James Allen Quinn

IPC分类号： C07D41304

CPC分类号： C07D413/04 ,  A01N43/80 ,  C07D413/14

摘要： Compounds with fungicidal properties having formula X is CH or nitrogen; R is (C1-C12)alkyl, halo(C1-C12)alkyl, (C2-C8)alkenyl, halo(C2-C8)alkenyl, (C2-C8)alkynyl, halo(C2-C8)alkynyl, (C1-C12)alkoxy(C1-C12)alkyl, (C3-C7)cycloalkyl, halo(C3-C7)cycloalkyl, (C3-C7)cycloalkyl(C1-C4)alkyl, aralkyl, aryloxy(C1-C4)alkyl or heterocyclic; R1 is aryl, heterocyclic or C(R6R7R8). R2 and R3 are each selected from hydrogen, (C1-C12)alkyl, halo(C1-C12)alkyl, (C1-C12)alkoxy, halo(C1-C12)alkoxy, (C3-C7)cycloalkyl, (C3-C7)cycloalkyl(C1-C4)alkyl, aryl, aralkyl, heterocyclic; cyano, and (C1-C4)alkoxycarbonyl; R4 and R5 are each selected from hydrogen, (C1-C12)alkyl, halo(C1-C12)alkyl, (C2-C8)alkenyl, halo(C2-C8)alkenyl, (C2-C8)alkynyl, halo(C2-C8)alkynyl, (C3-C7)cycloalkyl, halo(C3-C7)cycloalkyl, (C3-C7)cycloalkyl(C1-C4)alkyl, aryl, aryloxy(C1-C4)alkyl, aralkyl, heterocyclic, cyano, and (C1-C4)alkoxycarbonyl such that R4 and R5 are not both hydrogen; R6, R7, and R8 are each selected from hydrogen, (C1-C12)alkyl, (C2-C8)alkenyl, (C2-C8)alkynyl, (C1-C12)alkoxy(C1-C12)alkyl, (C3-C7)cycloalkyl, (C3-C7)cycloalkyl(C1-C4)alkyl, aryl, aralkyl, and heterocyclic(C1-C4)alkyl.

摘要翻译： 具有式X的具有杀真菌性的化合物是CH或氮; （C 2 -C 8）烯基，（C 2 -C 8）烯基，（C 2 -C 8）炔基，卤代（C 2 -C 8）炔基，（C 1 -C 8） C 1 -C 4烷基，C 1 -C 4烷基，C 1 -C 4烷基，（C 1 -C 4）烷基，C 3 -C 7环烷基， R1是芳基，杂环或C（R6R7R8）。 R2和R3分别选自氢，（C1-C12）烷基，卤代（C1-C12）烷基，（C1-C12）烷氧基，卤代（C1-C12）烷氧基，（C3-C7）环烷基，（C3-C7） ）环烷基（C 1 -C 4）烷基，芳基，芳烷基，杂环; 氰基和（C 1 -C 4）烷氧基羰基; R4和R5各自选自氢，（C1-C12）烷基，卤代（C1-C12）烷基，（C2-C8）烯基，卤代（C2-C8）烯基，（C2-C8）炔基， （C 3 -C 7）环烷基，（C 3 -C 7）环烷基，（C 3 -C 7）环烷基（C 1 -C 4）烷基，芳基，芳氧基（C 1 -C 4）

公开(公告)号：US06348627B1

公开(公告)日：2002-02-19

申请号：US09572487

申请日：2000-05-15

申请人： Ronald Ross, Jr. ,  Duyan Vuong Nguyen ,  Edward Michael Szapacs ,  Frisby Davis Smith ,  Steven Howard Shaber

发明人： Ronald Ross, Jr. ,  Duyan Vuong Nguyen ,  Edward Michael Szapacs ,  Frisby Davis Smith ,  Steven Howard Shaber

IPC分类号： C07C23305

CPC分类号： C07D213/53 ,  A01N37/36 ,  A01N37/50 ,  A01N43/08 ,  A01N43/10 ,  A01N43/36 ,  A01N43/40 ,  A01N43/42 ,  A01N43/50 ,  A01N43/54 ,  A01N43/56 ,  A01N43/58 ,  A01N43/60 ,  A01N43/76 ,  A01N43/78 ,  A01N43/80 ,  A01N53/00 ,  C07C251/60 ,  C07C2601/02 ,  C07C2602/02 ,  C07D213/62 ,  C07D215/12 ,  C07D231/12 ,  C07D233/64 ,  C07D237/08 ,  C07D239/26 ,  C07D239/34 ,  C07D241/12 ,  C07D261/08 ,  C07D263/32 ,  C07D275/02 ,  C07D277/28 ,  C07D307/52 ,  C07D307/56 ,  C07D333/22

摘要： Compounds with fungicidal and insecticidal properties having formula wherein X is N or CH; Z is O, S or NR8; A is hydrogen, halo, cyano, (C1-C12)alkyl, or (C1-C12)alkoxy; R1 and R8 are independently hydrogen or (C1-C4)alkyl; R2 is hydrogen, (C1-C12)alkyl, halo(C1-C12)alkyl, (C3-C7)cycloalkyl, halo(C3-C7)cycloalkyl, (C2-C8)alkenyl, halo(C2-C8)alkenyl, (C2-C8)alkynyl, halo(C2-C8)alkynyl, aryl, aralkyl, heterocyclic, heterocyclic(C1-C4)alkyl or C(R10)═N—OR9; R3 is hydrogen, (C1-C12)alkyl, halo(C1-C12)alkyl, (C3-C7)cycloalkyl, halo(C3-C7)cycloalkyl, (C2-C8)alkenyl, halo(C2-C8)alkenyl, (C2-C8)alkynyl, halo(C2-C8)alkynyl, aryl, aralkyl, aryl(C3-C7)cycloalkyl, heterocyclic or heterocyclic(C1-C4)alkyl; R4 and R5 are independently hydrogen, (C1-C12)alkyl, halo(C1-C12)alkyl, (C3-C7)cycloalkyl, halo(C3-C7)cycloalkyl, (C2-C8)alkenyl, halo(C2-C8)alkenyl, (C2-C8)alkynyl, halo(C2-C8)alkynyl, halo, cyano, (C1-C4)alkoxycarbonyl, aryl, aralkyl, aryl(C3-C7)cycloalkyl, heterocyclic or heterocyclic(C1-C4)alkyl; R6 is hydrogen, (C1-C12)alkyl, halo(C1-C12)alkyl, (C3-C7)cycloalkyl, halo(C3-C7)cycloalkyl, (C2-C8)alkenyl, halo(C2-C8)alkenyl, (C2-C8)alkynyl, halo(C2-C8)alkynyl, halo, cyano, (C1-C4)alkoxycarbonyl, aryl, aralkyl, aryl(C3-C7)cycloalkyl, heterocyclic or heterocyclic(C1-C4)alkyl; R7 is aryl, aralkyl, heterocyclic or heterocyclic(C1-C4)alkyl; R9 is hydrogen, (C1-C12)alkyl, halo(C1-C12)alkyl, (C2-C8)alkenyl, halo(C2-C8)alkenyl, (C2-C8)alkynyl, halo(C2-C8)alkynyl, (C1-C4)alkylcarbonyl, (C1-C4)alkoxycarbonyl, aryl, or aralkyl; and R10 is hydrogen, (C1-C12)alkyl, halo(C1-C12)alkyl, (C3-C7)cycloalkyl, halo(C3-C7)cycloalkyl, (C2-C8)alkenyl, halo(C2-C8)alkenyl, (C2-C8)alkynyl, halo(C2-C8)alkynyl, aryl, aralkyl, heterocyclic, or heterocyclic(C1-C4)alkyl.

摘要翻译： 具有杀虫和杀虫性质的化合物，其具有式（X）的化合物是N或CH; Z是O，S或NR8; A是氢，卤素，氰基，（C 1 -C 12）烷基或（C 1 -C 12）烷氧基; R1和R8独立地是氢或（C1-C4）烷基; （C 1 -C 12）烷基，（C 3 -C 7）环烷基，卤代（C 3 -C 7）环烷基，（C 2 -C 8）烯基，卤代（C 2 -C 8） C 2 -C 8炔基，卤代（C 2 -C 8）炔基，芳基，芳烷基，杂环，杂环（C 1 -C 4）烷基或C（R 10）= N-OR 9; （C 1 -C 12）烷基，（C 3 -C 7）环烷基，卤代（C 3 -C 7）环烷基，（C 2 -C 8）烯基，卤代（C 2 -C 8） C 2 -C 8）炔基，卤代（C 2 -C 8）炔基，芳基，芳烷基，芳基（C 3 -C 7）环烷基，杂环或杂环（C 1 -C 4） （C 1 -C 12）烷基，（C 3 -C 7）环烷基，卤代（C 3 -C 7）环烷基，（C 2 -C 8）烯基，卤代（C 2 -C 8） 烯基，（C 2 -C 8）炔基，卤代（C 2 -C 8）炔基，卤素，氰基，（C 1 -C 6）

公开(公告)号：US6121251A

公开(公告)日：2000-09-19

申请号：US938552

申请日：1997-09-26

申请人： Steven Howard Shaber ,  Edward Michael Szapacs ,  Ronald Ross

发明人： Steven Howard Shaber ,  Edward Michael Szapacs ,  Ronald Ross

IPC分类号： A01N43/58 ,  A01N47/24 ,  A01N55/10 ,  C07D237/04 ,  C07D237/14 ,  C07F9/6509 ,  C07D237/16

CPC分类号： C07D237/04 ,  A01N47/24 ,  C07D237/14 ,  C07F9/650911

摘要： Compounds with fungicidal and insecticidal properties having formula I ##STR1## wherein W is ##STR2## n is 0 or 1; Y is O, S, NR.sub.1, or R.sub.6 ;the ring bond containing R.sub.4 and R.sub.5 is a single or double bond;X is independently selected from hydrogen, halo, (C.sub.1 -C.sub.4)alkyl, (C.sub.1 -C.sub.4)alkoxy and --HC.dbd.CH--CH.dbd.CH-- thereby forming a napthyl ring;R is independently selected from (C.sub.1 -C.sub.12)alkyl and halo(C.sub.1 -C.sub.12)alkyl;R.sub.1 is independently selected from (C.sub.1 -C.sub.12)alkyl, (C.sub.2 -C.sub.8)alkenyl and aryl;R.sub.2 is independently selected from hydrogen, (C.sub.1 -C.sub.12)alkyl (C.sub.1 -C.sub.12)alkoxy, halo(C.sub.1 -C.sub.12)alkyl, halo(C.sub.1 -C.sub.12)alkoxy, hydroxy(C.sub.1 -C.sub.12)alkyl, (C.sub.1 -C.sub.12)alkoxy(C.sub.1 -C.sub.12)alkyl, (C.sub.1 -C.sub.12)alkoxycarbonyl(C.sub.1 -C.sub.12)alkyl, (C.sub.2 -C.sub.8)alkenyl, halo(C.sub.2 -C.sub.8)alkenyl, (C.sub.3 -C.sub.10)alkynyl, halo(C.sub.3 -C.sub.10)alkynyl, (C.sub.3 -C.sub.7)cycloalkyl, (C.sub.3 -C.sub.7)cycloalkyl(C.sub.1 -C.sub.4)alkyl, epoxy(C.sub.1 -C.sub.12)alkyl, PO(OR.sub.1).sub.2 (C.sub.1 -C.sub.12)alkyl, R.sub.1 S(O).sub.2 (C.sub.1 -C.sub.12)alkyl, (R.sub.1).sub.3 Si(C.sub.1 -C.sub.12)alkyl, aryl, aryloxy(C.sub.1 -C.sub.12)alkyl, arylcarbonyl(C.sub.1 -C.sub.12)alkyl, aralkyl, arylalkenyl, heterocyclic, heterocyclic (C.sub.1 -C.sub.12)alkyl, N-morpholino(C.sub.1 -C.sub.12)alkyl, N-piperidinyl(C.sub.1 -C.sub.12)alkyl;R.sub.4, and R.sub.5 are independently selected from hydrogen, halo, (C.sub.1 -C.sub.8)alkyl, (C.sub.1 -C.sub.8)alkoxy, cyano, halo(C.sub.1 -C.sub.12)alkyl, (C.sub.2 -C.sub.8)alkenyl, (C.sub.3 -C.sub.10)alkynyl, aryl and aralkyl; andR.sub.6 is (C.sub.1 -C.sub.12) alkylenyl and (C.sub.2 -C.sub.12)alkenylenyl.

摘要翻译： 具有式I的具有杀真菌性和杀虫性的化合物，其中W是n是0或1; Y是O，S，NR1或R6; 含有R 4和R 5的环键是单键或双键; X独立地选自氢，卤素，（C 1 -C 4）烷基，（C 1 -C 4）烷氧基和-HC = CH-CH = CH-，从而形成萘基环; R独立地选自（C 1 -C 12）烷基和卤代（C 1 -C 12）烷基; R 1独立地选自（C 1 -C 12）烷基，（C 2 -C 8）烯基和芳基; R2是独立选自氢，（C1-C12）烷基（C1-C12）烷氧基，卤代（C1-C12）烷基，卤代（C1-C12）烷氧基，羟基（C1-C12）烷基，（C1-C12）烷氧基 （C1-C12）烷基，（C1-C12）烷氧基羰基（C1-C12）烷基，（C2-C8）烯基，卤代（C2-C8）烯基，（C3-C10）炔基，卤代（C3-C10）炔基， （C 3 -C 7）环烷基，（C 3 -C 7）环烷基（C 1 -C 4）烷基，环氧（C 1 -C 12）烷基，PO（OR 1）2（C 1 -C 12）烷基， 烷基，（R1）3Si（C1-C12）烷基，芳基，芳氧基（C1-C12）烷基，芳基羰基（C1-C12）烷基，芳烷基，芳基烯基，杂环，杂环（C1-C12）烷基，N-吗啉代 -C 12）烷基，N-哌啶基（C 1 -C 12）烷基; （C 1 -C 8）烷氧基，氰基，卤代（C 1 -C 12）烷基，（C 2 -C 8）烯基，（C 3 -C 10）炔基， 芳基和芳烷基; 并且R 6是（C 1 -C 12）亚烷基和（C 2 -C 12）烯基。

公开(公告)号：US6121268A

公开(公告)日：2000-09-19

申请号：US197637

申请日：1998-11-23

申请人： Ronald Ross ,  Ted Tsutomo Fujimoto ,  Edward Michael Szapacs ,  Steven Howard Shaber

发明人： Ronald Ross ,  Ted Tsutomo Fujimoto ,  Edward Michael Szapacs ,  Steven Howard Shaber

IPC分类号： A01N47/24 ,  C07C271/28 ,  C07D213/50 ,  C07D239/26 ,  C07D333/22 ,  C07C271/12 ,  A01N37/08 ,  A01N37/12 ,  A01N43/40 ,  C07C271/14

CPC分类号： C07D239/26 ,  A01N47/24 ,  C07C271/28 ,  C07D213/50 ,  C07D333/22 ,  C07C2101/02 ,  C07C2101/08 ,  C07C2101/14

摘要： Compounds with fungicidal properties having formula I ##STR1## where m and n are 0 or 1 provided that m+n is 1; X is hydrogen, halo, (C.sub.1 -C.sub.4)alkyl, or (C.sub.1 -C.sub.4)alkoxy; R is an optionally-substituted alkyl, cycloalkyl, alkenyl, alkynyl, alkoxy, aryl, aralkyl, or heterocyclic group; R.sub.1 and R.sub.2 are hydrogen, optionally-substituted alkyl, cycloalkyl, cyano, carboxy alkyl, or aryl; at least one of R.sub.1 and R.sub.2 is hydrogen; and R.sub.3 is alkyl or haloalkyl.

摘要翻译： 具有式I的具有杀真菌性的化合物，其中m和n为0或1，条件是m + n为1; X是氢，卤素，（C 1 -C 4）烷基或（C 1 -C 4）烷氧基; R是任选取代的烷基，环烷基，烯基，炔基，烷氧基，芳基，芳烷基或杂环基; R 1和R 2是氢，任选取代的烷基，环烷基，氰基，羧基烷基或芳基; R1和R2中的至少一个是氢; 并且R 3是烷基或卤代烷基。