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公开(公告)号:US20110171739A1
公开(公告)日:2011-07-14
申请号:US13063525
申请日:2009-09-23
申请人: Steven John Kemp , Lynda Jane Storey , John Mervyn David , Janet Richard , Charles Robert Harrington , Claude Michael Wischik , Scott Clunas , Tobias Kerst Heinrich
发明人: Steven John Kemp , Lynda Jane Storey , John Mervyn David , Janet Richard , Charles Robert Harrington , Claude Michael Wischik , Scott Clunas , Tobias Kerst Heinrich
IPC分类号: G01N33/50 , C07D277/66 , C07D417/12 , C07D513/04 , C07D471/04
CPC分类号: G01N33/6896 , C07D277/66 , C07D417/12 , C07D471/04 , C07D487/04 , C07D513/04 , G01N2333/4709 , G01N2800/2821 , Y10T436/14 , Y10T436/147777 , Y10T436/17 , Y10T436/18
摘要: Provided are certain benzothiazole, imidazothiazole, imidazopyrimidine and imidazopyridine compounds, including, for example: formula (I) and pharmaceutically and physiologically acceptable salts, hydrates, and solvates thereof. Such compounds can be used as diagnostic ligands or labels of tau protein and PHF.
摘要翻译: 提供某些苯并噻唑,咪唑并噻唑,咪唑并嘧啶和咪唑并吡啶化合物,包括例如:式(I)及其药学上和生理上可接受的盐,水合物和溶剂化物。 此类化合物可用作tau蛋白和PHF的诊断配体或标记。
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公开(公告)号:US08895313B2
公开(公告)日:2014-11-25
申请号:US13063525
申请日:2009-09-23
申请人: Steven John Kemp , Lynda Jane Storey , John Mervyn David Storey , Janet Rickard , Charles Robert Harrington , Claude Michel Wischik , Scott Clunas , Tobias Kerst Heinrich
发明人: Steven John Kemp , Lynda Jane Storey , John Mervyn David Storey , Janet Rickard , Charles Robert Harrington , Claude Michel Wischik , Scott Clunas , Tobias Kerst Heinrich
IPC分类号: G01N33/50 , C07D277/66 , C07D417/12 , C07D513/04 , C07D471/04 , C07D487/04 , G01N33/68
CPC分类号: G01N33/6896 , C07D277/66 , C07D417/12 , C07D471/04 , C07D487/04 , C07D513/04 , G01N2333/4709 , G01N2800/2821 , Y10T436/14 , Y10T436/147777 , Y10T436/17 , Y10T436/18
摘要: Provided are certain benzothiazole, imidazothiazole, imidazopyrimidine and imidazopyridine compounds, including, for example: formula (I) and pharmaceutically and physiologically acceptable salts, hydrates, and solvates thereof. Such compounds can be used as diagnostic ligands or labels of tau protein and PHF.
摘要翻译: 提供某些苯并噻唑,咪唑并噻唑,咪唑并嘧啶和咪唑并吡啶化合物,包括例如:式(I)及其药学上和生理上可接受的盐,水合物和溶剂化物。 此类化合物可用作tau蛋白和PHF的诊断配体或标记。
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