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1.发明申请公开(公告)号：US20060263813A1
公开(公告)日：2006-11-23
申请号：US11433191
申请日：2006-05-11
申请人： Steven Rosenberg , Preeti Lal , Kirk Fry , Tod Klingler , Dirk Walther , Robert Woodward
发明人： Steven Rosenberg , Preeti Lal , Kirk Fry , Tod Klingler , Dirk Walther , Robert Woodward
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6883 , C12Q2600/118 , C12Q2600/158
摘要： Methods useful in monitoring the functional status of a transplant in a patient by detecting the expression levels of gene panels are described herein. Algorithms for analysis of the expression for monitoring the functional status of transplants are also described.
摘要翻译： 本文描述了通过检测基因片段的表达水平来监测患者中移植物的功能状态的方法。 还描述了用于分析用于监测移植物的功能状态的表达的算法。
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公开(公告)号：US20110104697A1
公开(公告)日：2011-05-05
申请号：US12985314
申请日：2011-01-05
申请人： Jay WOHLGEMUTH , Kirk Fry , Robert Woodward , Ngoc Ly , James Prentice , MacDonald Morris , Steven Rosenberg
发明人： Jay WOHLGEMUTH , Kirk Fry , Robert Woodward , Ngoc Ly , James Prentice , MacDonald Morris , Steven Rosenberg
CPC分类号： C12Q1/6881 , C12Q1/6883 , C12Q1/6888 , C12Q2600/112 , C12Q2600/158 , G01N33/564 , Y10T436/143333
摘要： Methods of diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection, in a patient by detecting the expression level of one or more genes in a patient, are described. Diagnostic oligonucleotides for diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection and kits or systems containing the same are also described.
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公开(公告)号：US20100151467A1
公开(公告)日：2010-06-17
申请号：US12584615
申请日：2009-09-08
申请人： Jay Wohlgemuth , Kirk Fry , Robert Woodward , Ngoc Ly , James Prentice , MacDonald Morris , Steven Rosenberg
发明人： Jay Wohlgemuth , Kirk Fry , Robert Woodward , Ngoc Ly , James Prentice , MacDonald Morris , Steven Rosenberg
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6881 , C12Q1/6883 , C12Q1/6888 , C12Q2600/112 , C12Q2600/158 , G01N33/564 , Y10T436/143333
摘要： Methods of diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection, in a patient by detecting the expression level of one or more genes in a patient, are described. Diagnostic oligonucleotides for diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection and kits or systems containing the same are also described.
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4.发明申请公开(公告)号：US20100099098A1
公开(公告)日：2010-04-22
申请号：US12544182
申请日：2009-08-19
申请人： Jay Wohlgemuth , Kirk Fry , Robert Woodward , Ngoc Ly , James Prentice , MacDonald Morris , Steven Rosenberg
发明人： Jay Wohlgemuth , Kirk Fry , Robert Woodward , Ngoc Ly , James Prentice , MacDonald Morris , Steven Rosenberg
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6883 , C12Q1/6881 , C12Q1/6888 , C12Q2600/158 , G01N33/564 , G01N33/6863 , G01N2800/245
摘要： Methods of diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection, in a patient by detecting the expression level of one or more genes in a patient, are described. Diagnostic oligonucleotides for diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection and kits or systems containing the same are also described.
摘要翻译： 描述了通过检测患者中一种或多种基因的表达水平来诊断或监测患者中移植排斥，特别是心脏移植排斥的方法。 还描述了用于诊断或监测移植排斥反应的诊断性寡核苷酸，特别是心脏移植排斥反应及其含有该移植排斥反应的试剂盒或系统。
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5.发明授权公开(公告)号：US07691569B2
公开(公告)日：2010-04-06
申请号：US10511937
申请日：2003-04-24
申请人： Jay Wohlgemuth , Kirk Fry , Robert Woodward , Ngoc Ly , James Prentice , MacDonald Morris , Steven Rosenberg
发明人： Jay Wohlgemuth , Kirk Fry , Robert Woodward , Ngoc Ly , James Prentice , MacDonald Morris , Steven Rosenberg
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6883 , C12Q1/6881 , C12Q1/6888 , C12Q2600/158 , G01N33/564 , G01N33/6863 , G01N2800/245
摘要： Methods of diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection, in a patient by detecting the expression level of one or more genes in a patient, are described. Diagnostic oligonucleotides for diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection and kits or systems containing the same are also described.
摘要翻译： 描述了通过检测患者中一种或多种基因的表达水平来诊断或监测患者中移植排斥，特别是心脏移植排斥的方法。 还描述了用于诊断或监测移植排斥反应的诊断性寡核苷酸，特别是心脏移植排斥反应及其含有该移植排斥反应的试剂盒或系统。
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6.发明申请METHODS AND COMPOSITIONS FOR DIAGNOSING AND MONITORING TRANSPLANT REJECTION 审中-公开用于诊断和监测移植物排斥的方法和组合物公开(公告)号：US20110306518A1
公开(公告)日：2011-12-15
申请号：US13215139
申请日：2011-08-22
申请人： Jay WOHLGEMUTH , Kirk Fry , Robert Woodward , Ngoc Ly , James Prentice , MacDonald Morris , Steven Rosenberg
发明人： Jay WOHLGEMUTH , Kirk Fry , Robert Woodward , Ngoc Ly , James Prentice , MacDonald Morris , Steven Rosenberg
CPC分类号： C12Q1/6881 , C12Q1/6883 , C12Q1/6888 , C12Q2600/112 , C12Q2600/158 , G01N33/564 , Y10T436/143333
摘要： Methods of diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection, in a patient by detecting the expression level of one or more genes in a patient, are described. Diagnostic oligonucleotides for diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection and kits or systems containing the same are also described.
摘要翻译： 描述了通过检测患者中一种或多种基因的表达水平来诊断或监测患者中移植排斥，特别是心脏移植排斥的方法。 还描述了用于诊断或监测移植排斥反应的诊断性寡核苷酸，特别是心脏移植排斥反应及其含有该移植排斥反应的试剂盒或系统。
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公开(公告)号：US07892745B2
公开(公告)日：2011-02-22
申请号：US12584615
申请日：2009-09-08
申请人： Jay Wohlgemuth , Kirk Fry , Robert Woodward , Ngoc Ly , James Prentice , MacDonald Morris , Steven Rosenberg
发明人： Jay Wohlgemuth , Kirk Fry , Robert Woodward , Ngoc Ly , James Prentice , MacDonald Morris , Steven Rosenberg
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6881 , C12Q1/6883 , C12Q1/6888 , C12Q2600/112 , C12Q2600/158 , G01N33/564 , Y10T436/143333
摘要： Methods of diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection, in a patient by detecting the expression level of one or more genes in a patient, are described. Diagnostic oligonucleotides for diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection and kits or systems containing the same are also described.
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8.发明申请公开(公告)号：US20060088836A1
公开(公告)日：2006-04-27
申请号：US10511937
申请日：2003-04-24
申请人： Jay Wohlgemuth , Kirk Fry , Robert Woodward , Ngoc Ly , James Prentice , MacDonald Morris , Steven Rosenberg
发明人： Jay Wohlgemuth , Kirk Fry , Robert Woodward , Ngoc Ly , James Prentice , MacDonald Morris , Steven Rosenberg
CPC分类号： C12Q1/6883 , C12Q1/6881 , C12Q1/6888 , C12Q2600/158 , G01N33/564 , G01N33/6863 , G01N2800/245
摘要： Methods of diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection, in a patient by detecting the expression level of one or more genes in a patient, are described. Diagnostic oligonucleotides for diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection and kits or systems containing the same are also described.
摘要翻译： 描述了通过检测患者中一种或多种基因的表达水平来诊断或监测患者中移植排斥，特别是心脏移植排斥的方法。 还描述了用于诊断或监测移植排斥反应的诊断性寡核苷酸，特别是心脏移植排斥反应及其含有该移植排斥反应的试剂盒或系统。
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9.发明授权公开(公告)号：US07879556B2
公开(公告)日：2011-02-01
申请号：US12855178
申请日：2010-08-12
申请人： Jay Wohlgemuth , Kirk Fry , Robert Woodward , Ngoc Ly , James Prentice , MacDonald Morris , Steven Rosenberg
发明人： Jay Wohlgemuth , Kirk Fry , Robert Woodward , Ngoc Ly , James Prentice , MacDonald Morris , Steven Rosenberg
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6881 , C12Q1/6883 , C12Q1/6888 , C12Q2600/112 , C12Q2600/158 , G01N33/564 , Y10T436/143333
摘要： Methods of diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection, in a patient by detecting the expression level of one or more genes in a patient, are described. Diagnostic oligonucleotides for diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection and kits or systems containing the same are also described.
摘要翻译： 描述了通过检测患者中一种或多种基因的表达水平来诊断或监测患者中移植排斥，特别是心脏移植排斥的方法。 还描述了用于诊断或监测移植排斥反应的诊断性寡核苷酸，特别是心脏移植排斥反应及其含有该移植排斥反应的试剂盒或系统。
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公开(公告)号：US20100317018A1
公开(公告)日：2010-12-16
申请号：US12855178
申请日：2010-08-12
申请人： Jay WOHLGEMUTH , Kirk Fry , Robert Woodward , Ngoc Ly , James Prentice , MacDonald Morris , Steven Rosenberg
发明人： Jay WOHLGEMUTH , Kirk Fry , Robert Woodward , Ngoc Ly , James Prentice , MacDonald Morris , Steven Rosenberg
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6881 , C12Q1/6883 , C12Q1/6888 , C12Q2600/112 , C12Q2600/158 , G01N33/564 , Y10T436/143333
摘要： Methods of diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection, in a patient by detecting the expression level of one or more genes in a patient, are described. Diagnostic oligonucleotides for diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection and kits or systems containing the same are also described.
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