Pharmaceutical compositions and methods for treating multidrug resistant cancer
    2.
    发明申请
    Pharmaceutical compositions and methods for treating multidrug resistant cancer 审中-公开
    用于治疗多药耐药性癌症的药物组合物和方法

    公开(公告)号:US20060252714A1

    公开(公告)日:2006-11-09

    申请号:US10542602

    申请日:2004-01-19

    Abstract: The invention relates to a pharmaceutical composition comprising i) ketotifen or an analog thereof and ii) a chemotherapeutic drug subject to multi-drug resistance by P-gp, such as doxorubicin or an analog thereof. The pharmaceutical composition is useful for treating cancer. The pharmaceutical composition is also useful for i) preventing or treating multi-drug resistance in a subject or ii) preventing a chemotherapeutic drug subject to multi-drug resistance by P-gp induced cardiac tissue damage in a subject, such as doxorubicin or an analog thereof. The invention relates to a pharmaceutical composition comprising i) ketotifen or an analog thereof and ii) a chemotherapeutic drug subject to multi-drug resistance by P-gp, such as doxorubicin or an analog thereof. The pharmaceutical composition is useful for treating cancer. The pharmaceutical composition is also useful for i) preventing or treating multiamrg resistance in a subject or ii) preventing a chemotherapeutic drug subject to multi-drug resistance by P-gp induced cardiac tissue damage in a subject, such as doxorubicin or an analog thereof.

    Abstract translation: 本发明涉及药物组合物,其包含i)酮替芬或其类似物,和ii)受P-gp多药耐药的化疗药物,例如多柔比星或其类似物。 该药物组合物可用于治疗癌症。 药物组合物还可用于i)预防或治疗受试者的多重耐药性,或ii)通过P-gp诱导的受试者的心脏组织损伤(例如多柔比星或类似物)预防受多药耐药性的化疗药物 其中。 本发明涉及药物组合物,其包含i)酮替芬或其类似物,和ii)受P-gp多药耐药的化疗药物,例如多柔比星或其类似物。 该药物组合物可用于治疗癌症。 药物组合物还可用于i)预防或治疗受试者的多抗药性,或ii)通过受试者(例如多柔比星或其类似物)中的P-gp诱导的心脏组织损伤来预防受多种药物抗性的化疗药物。

    Wheeled And Compressible Luggage
    3.
    发明公开

    公开(公告)号:US20240065402A1

    公开(公告)日:2024-02-29

    申请号:US17861184

    申请日:2022-07-09

    Applicant: Stuart Berger

    Inventor: Stuart Berger

    Abstract: The present invention relates to an article of luggage that is configured to be conveniently rolled or wheeled about when in use as well as readily stored when empty and not in use. The luggage has wheels that are placed on the back side of the luggage, such that in use the luggage is wheeled about in a horizontal position. This position also provides use of the luggage as a cart for additional luggage or items that can be placed or stacked on the luggage while horizontal. The telescopic handle that is mounted in the back of the luggage is rotatable to an upward position when fully extended, to allow a user to ready pull and/or push the horizontal luggage. The luggage further has sides that are compressible/collapsible when not in use, to allow the height of the luggage to be reduced and therefore easier to store by occupying less space than the full size, fully expanded luggage. In addition, the luggage optionally has one or more outlets for charging portable electronic devices.

    Holder device for paper articles and writing instruments
    4.
    发明授权
    Holder device for paper articles and writing instruments 失效
    用于纸制品和书写工具的支架装置

    公开(公告)号:US4100684A

    公开(公告)日:1978-07-18

    申请号:US698073

    申请日:1976-06-21

    Applicant: Stuart Berger

    Inventor: Stuart Berger

    CPC classification number: A45C11/36 Y10S206/818

    Abstract: A holder device for holding paper articles and writing instruments includes a housing having a pair of compartments therein. A permanent magnet is mounted on the housing and is removably received on a ferrous metallic bar which is mounted on a stationary object. An ejector assembly is contained in one of the compartments for ejecting the writing instruments from the compartment.

    Abstract translation: 用于保持纸制品和书写工具的保持装置包括其中具有一对隔室的壳体。 永磁体安装在壳体上,并可移除地容纳在安装在静止物体上的铁金属棒上。 喷射器组件包含在隔室中的一个中,用于将书写工具从隔室中排出。

    Medicine caddy
    5.
    发明授权
    Medicine caddy 失效
    药盒

    公开(公告)号:US07568582B1

    公开(公告)日:2009-08-04

    申请号:US11314425

    申请日:2005-12-21

    Applicant: Stuart Berger

    Inventor: Stuart Berger

    CPC classification number: A47B49/00

    Abstract: Medicine caddies store and organize medicines. A bottom tier with a first shelf, a first wall, and a first divider is slidably and rotatably mounted on a base. A second tier with a second shelf, a second wall, and a second divider is attached to the first wall. Barriers enclose the sides of the first and second walls. Cutouts present in the middle of the first and second walls allow divider hooks on the dividers to be slidably and removably attached to the first and second walls. Barrier slots in the top of the barriers slidably and removably receive barrier hooks attached to the dividers. A second embodiment has a rotation joint between the first and second walls and has its dividers slidably attached to only the first and second walls. Tabs are provided as a perforated sheet and are attached to the barriers by tab holders to identify medicines.

    Abstract translation: 医药店储存和组织药物。 具有第一搁板,第一壁和第一分隔件的底层可滑动地且可旋转地安装在基座上。 具有第二搁架,第二壁和第二分隔件的第二层连接到第一壁。 障碍物包围第一和第二壁的两侧。 存在于第一和第二壁的中间的切口允许分隔器上的分隔钩可滑动地和可拆卸地附接到第一和第二壁。 障碍物顶部的阻挡槽可滑动地并且可移除地接收附接到分隔器的阻挡钩。 第二实施例在第一和第二壁之间具有旋转接头,并且其分隔件可滑动地附接到仅第一壁和第二壁。 标签提供为穿孔片材,并通过片状支架附着到障碍物上以鉴定药物。

    Liposomal compositions for parenteral delivery of agents
    6.
    发明申请
    Liposomal compositions for parenteral delivery of agents 审中-公开
    用于胃肠外递送药剂的脂质体组合物

    公开(公告)号:US20090028931A1

    公开(公告)日:2009-01-29

    申请号:US11883255

    申请日:2006-01-30

    CPC classification number: A61K9/1271 A61K9/1278 A61K31/4174

    Abstract: The invention provides methods and compositions for loading an agent, such as econazole, onto a liposome for parental delivery. The loading of the agent into a liposome comprises combining the agent with a micelle-forming compound to form a micelle including the agent, where the agent is releasable from the micelle-forming compound, and adding the micelle to the liposome, where the micelle combines with the liposome such that the agent is loaded into the liposome to form a loaded liposome. The methods are suitable for the loading of poorly soluble agents onto liposome.

    Abstract translation: 本发明提供了用于将药剂(例如益康唑)加载到用于亲代递送的脂质体上的方法和组合物。 将试剂加载到脂质体中包括将试剂与胶束形成化合物组合以形成包含试剂的胶束,其中试剂可从胶束形成化合物释放,并将胶束加入脂质体中,其中胶束结合 与脂质体一起使得试剂加载到脂质体中以形成负载的脂质体。 该方法适用于将难溶性物质加载到脂质体上。

    Device for Dental Irrigation
    7.
    发明公开

    公开(公告)号:US20240180678A1

    公开(公告)日:2024-06-06

    申请号:US17326370

    申请日:2021-05-21

    Applicant: Stuart Berger

    Inventor: Stuart Berger

    CPC classification number: A61C17/024 A61C2204/002

    Abstract: The presently disclosed dental irrigation device projects irrigates and cleans teeth by directing fluid onto the surfaces of a user's teeth and the interproximal spaces between a user's teeth and gum line. The device comprises two hollow U-shaped manifolds that are arranged in a back to back configuration, with one manifold pointing up and one manifold pointing down. Each manifold has an orifice located on each interior face that is used as a fluid jet to irrigate surfaces between teeth and gum line. The dental irrigation device preferably is part of an overall, self-contained device that includes the dental irrigation device, a fluid source/container, a pump that provides fluid from the container to the dental irrigation device, and a dry battery, independent power source. The self-contained device allows for handheld, cords and/or tubing free use of the self-contained device and accordingly, dental irrigation device.

    Portable, collapsible footstool
    8.
    发明授权

    公开(公告)号:US10918215B1

    公开(公告)日:2021-02-16

    申请号:US17011179

    申请日:2020-09-03

    Applicant: Stuart Berger

    Inventor: Stuart Berger

    Abstract: The presently disclosed footstool comprises a collapsible footstool that is useful for conveniently placing one's foot into comfortable reach to facilitate personal grooming, shoe tying, and the like. The collapsible footrest features a height adjustable footrest that positions one's toes at different selected heights relative to the footstool's table top. The table top includes raised edges that form a tray for holding personal grooming tools and the like. The table top likewise preferably includes a drawer for storing tools and like when not in use. The table top further includes one or more USB ports that power/support optional accessories that plug into the table top, such as a light, magnifying lens, and/or a fan.

    Ice Formation and Storage Device
    9.
    发明申请

    公开(公告)号:US20190285326A1

    公开(公告)日:2019-09-19

    申请号:US15956028

    申请日:2018-04-18

    Applicant: Stuart Berger

    Inventor: Stuart Berger

    Abstract: The present invention relates to an ice formation device that can be used to form and store ice and ice cubes. The ice formation device includes an outer bucket, a cylinder, and a lid. The cylinder is sized to snugly fit within the outer bucket to form a water tight seal with the outer bucket. The outer bucket has channels and pockets that are filled with water when the cylinder is inserted into the outer bucket, and the water is frozen to form ice/ice cubes. The cylinder can be re-inserted into the outer bucket after ice is formed and stored in the outer bucket, to allow for subsequent ice formation when the outer bucket contains ice cubes that have been released from the outer bucket's channels and pockets. The ice formation device can also be used as an ice bucket for chilling a bottle or other items that can be placed inside the cylinder once ice has been formed between the cylinder and the outer bucket.

    Object storage tray
    10.
    发明授权
    Object storage tray 失效
    对象存储托盘

    公开(公告)号:US07886917B1

    公开(公告)日:2011-02-15

    申请号:US12011295

    申请日:2008-01-25

    Applicant: Stuart Berger

    Inventor: Stuart Berger

    CPC classification number: A47B81/04 A47B45/00 A47B88/90 A47J47/16

    Abstract: Object storage trays provide a tray for storing pots, pans, and their lids. First and second top members and first and second end members form a generally rectangular frame attached to a first center member, a first cross member, and a second cross member. Generally sinusoidal longitudinal members are attached to the first cross member, first center member, and second cross member. Glider brackets are attached beneath the longitudinal members to connect gliders to the object storage tray. Dividers mounted on sliding pivots are attached to the first center member and have lid handle notches in their middles. A telescoping embodiment of the invention is also disclosed that permits adjustments to the width of the object storage tray.

    Abstract translation: 物体储存托盘提供一个用于储存罐,平底锅和盖子的托盘。 第一和第二顶部构件和第一和第二端构件形成附接到第一中心构件,第一横向构件和第二横向构件的大致矩形框架。 通常,正弦曲线纵向构件附接到第一横向构件,第一中心构件和第二横向构件。 滑翔机支架连接在纵向构件下方,以将滑翔机连接到物体存储托盘。 安装在滑动枢轴上的分隔件安装在第一中心构件上,并且在其中间具有盖把手凹口。 还公开了本发明的伸缩实施例,其允许调节对象存储托盘的宽度。

Patent Agency Ranking