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公开(公告)号:US20090123518A1
公开(公告)日:2009-05-14
申请号:US12288537
申请日:2008-10-20
申请人: Su Il Yum , Sanjay Goskonda , Huey-Ching Su
发明人: Su Il Yum , Sanjay Goskonda , Huey-Ching Su
CPC分类号: A61K9/0024 , A61K9/0004 , A61K38/09
摘要: Disclosed solid water permeable implants that include a water permeable polymer and an osmotically active drug formulation that comprises a drug; wherein the solid water permeable implant has a ratio R of bulk density of the solid water permeable implant to osmotic pressure of the drug formulation wherein R is greater than about 0.244 grams/milliliter-atm. Also disclosed are methods of making and using such solid water permeable implants.
摘要翻译: 公开的固体水可渗透植入物,其包括水可渗透聚合物和包含药物的渗透活性药物制剂; 其中固体水可渗透植入物具有固体水可渗透植入物的体积密度与药物制剂的渗透压的比R,其中R大于约0.244克/毫升。 还公开了制造和使用这种固体水可渗透植入物的方法。
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公开(公告)号:US20120225033A1
公开(公告)日:2012-09-06
申请号:US13304174
申请日:2011-11-23
申请人: William W. van Osdol , Su il Yum , Felix Theeuwes , Michael Sekar , John Gibson , Keith Branham , Huey-Ching Su
发明人: William W. van Osdol , Su il Yum , Felix Theeuwes , Michael Sekar , John Gibson , Keith Branham , Huey-Ching Su
IPC分类号: A61K38/27 , A61K38/16 , A61K38/26 , A61K38/21 , A61K31/7105
CPC分类号: A61K38/212 , A61K9/0019 , A61K31/7052 , A61K38/26 , A61K38/27 , A61K47/14 , A61K47/26 , A61K47/34 , A61K47/52 , A61K47/541 , A61K47/64
摘要: The present disclosure provides a biodegradable drug delivery composition including a vehicle and an insoluble component comprising beneficial agent dispersed in the vehicle. Typically, the composition is not an emulsion, but has a low viscosity and further provides for minimized initial burst and sustained release of the beneficial agent over time. Also provided, are kits including the biodegradable drug delivery composition or components thereof, as well as methods of making and using the biodegradable drug delivery composition.
摘要翻译: 本公开提供了包含载体和包含分散在载体中的有益剂的不溶性组分的生物可降解药物递送组合物。 通常,组合物不是乳液,而是具有低粘度,并进一步提供有益剂随时间的最小化的初始爆发和持续释放。 还提供了包括可生物降解的药物递送组合物或其组分的试剂盒,以及制备和使用可生物降解的药物递送组合物的方法。
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公开(公告)号:US08415401B2
公开(公告)日:2013-04-09
申请号:US12315868
申请日:2008-12-05
申请人: Su Il Yum , Wendy Chao , Huey-Ching Su , Roger Fu , Michael Zamloot
发明人: Su Il Yum , Wendy Chao , Huey-Ching Su , Roger Fu , Michael Zamloot
IPC分类号: A61K47/00
CPC分类号: A61K9/4866 , A61K9/48 , A61K9/4858 , A61K31/137 , A61K31/4402 , A61K31/4458 , A61K31/485
摘要: Abuse-resistant oral dosage forms suitable for administration of pharmacologically active agents are provided.
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公开(公告)号:US20090215808A1
公开(公告)日:2009-08-27
申请号:US12315868
申请日:2008-12-05
申请人: Su Il Yum , Wendy Chao , Huey-Ching Su , Roger Fu , Michael Zamloot
发明人: Su Il Yum , Wendy Chao , Huey-Ching Su , Roger Fu , Michael Zamloot
IPC分类号: A61K31/4355 , A61K31/34 , A61K47/38 , A61K47/04
CPC分类号: A61K9/4866 , A61K9/48 , A61K9/4858 , A61K31/137 , A61K31/4402 , A61K31/4458 , A61K31/485
摘要: Abuse-resistant oral dosage forms suitable for administration of pharmacologically active agents are provided.
摘要翻译: 提供了适合施用药理活性剂的耐药性口服剂型。
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公开(公告)号:US20100260844A1
公开(公告)日:2010-10-14
申请号:US12590195
申请日:2009-11-03
IPC分类号: A61K31/445 , A61K9/00 , A61P25/00
CPC分类号: A61K31/4458 , A61K9/0053 , A61K9/1617 , A61K9/1623 , A61K9/4808 , A61K9/4858 , A61K9/5084
摘要: Controlled release oral dosage forms suitable for administration of methylphenidate are provided. Abuse-resistant controlled release oral dosage forms suitable for administration of methylphenidate are also provided. Methods of treating ADD and ADHD using the oral dosage forms are also provided.
摘要翻译: 提供了适用于哌甲酯施用的控释口服剂型。 还提供了适合施用哌甲酯的耐药性控释口服剂型。 还提供了使用口服剂型治疗ADD和ADHD的方法。
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