Biodegradable implants with controlled bulk density
    1.
    发明申请
    Biodegradable implants with controlled bulk density 审中-公开
    具有可控堆积密度的可生物降解植入物

    公开(公告)号:US20090123518A1

    公开(公告)日:2009-05-14

    申请号:US12288537

    申请日:2008-10-20

    IPC分类号: A61F2/00 A61K38/22

    摘要: Disclosed solid water permeable implants that include a water permeable polymer and an osmotically active drug formulation that comprises a drug; wherein the solid water permeable implant has a ratio R of bulk density of the solid water permeable implant to osmotic pressure of the drug formulation wherein R is greater than about 0.244 grams/milliliter-atm. Also disclosed are methods of making and using such solid water permeable implants.

    摘要翻译: 公开的固体水可渗透植入物,其包括水可渗透聚合物和包含药物的渗透活性药物制剂; 其中固体水可渗透植入物具有固体水可渗透植入物的体积密度与药物制剂的渗透压的比R,其中R大于约0.244克/毫升。 还公开了制造和使用这种固体水可渗透植入物的方法。