公开(公告)号：US5763477A

公开(公告)日：1998-06-09

申请号：US471639

申请日：1995-06-06

申请人： Subrahmanyam Duvvuri ,  Venkateswarlu Akella ,  Sharma Manohar Vedula ,  Ramachandra Puranik ,  Raghavendra Madhva Sattegeri

发明人： Subrahmanyam Duvvuri ,  Venkateswarlu Akella ,  Sharma Manohar Vedula ,  Ramachandra Puranik ,  Raghavendra Madhva Sattegeri

IPC分类号： C07D305/14 ,  C07D413/12 ,  A61K21/335 ,  C07D321/10

CPC分类号： C07D413/12 ,  C07D305/14

摘要： Novel taxane derivatives and intermediates having the formula 1. ##STR1## and a process for the preparation of the compounds of the formula 1 from 14-.beta.-hydroxy-10-deacetylbaccatin III of formula 2 ##STR2## and pharmaceutically acceptable compositions containing the taxane derivatives and intermediates of formula 1.

摘要翻译： 具有式1的新型紫杉烷衍生物和中间体。＆lt; IMAGE＆gt; 1和由式2的14-β-羟基-10-脱乙酰基浆果赤霉素III制备式1化合物的方法和含有 式1的紫杉烷衍生物和中间体。