公开(公告)号：US12103937B2

公开(公告)日：2024-10-01

申请号：US18105712

申请日：2023-02-03

申请人： Sudo Biosciences Limited

发明人： Anjali Pandey ,  Gregory Dietsch ,  Seetharaman Manojveer ,  Mahesh Thakkar ,  Athisayamani Jeyaraj Duraiswamy ,  Sukesh Kalva

IPC分类号： A61K31/16 ,  A61K9/00 ,  A61K9/06 ,  A61K9/20 ,  C07C233/64 ,  C07D471/04 ,  C07D471/14 ,  C07D487/04 ,  C07D498/04

CPC分类号： C07D498/04 ,  A61K9/0014 ,  A61K9/0048 ,  A61K9/0056 ,  A61K9/008 ,  A61K9/06 ,  A61K9/2054 ,  C07D471/04 ,  C07D471/14 ,  C07D487/04 ,  C07B2200/05

摘要： Described herein are compounds of Formula (XIV) that are TYK2 inhibitors, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders that would benefit from modulation of TYK2 activity.

公开(公告)号：US12084458B2

公开(公告)日：2024-09-10

申请号：US18105708

申请日：2023-02-03

申请人： Sudo Biosciences Limited

发明人： Anjali Pandey ,  Gregory Dietsch ,  Seetharaman Manojveer ,  Mahesh Thakkar ,  Athisayamani Jeyaraj Duraiswamy ,  Sukesh Kalva

IPC分类号： A61K31/16 ,  A61K9/00 ,  A61K9/06 ,  A61K9/20 ,  C07C233/64 ,  C07D471/04 ,  C07D471/14 ,  C07D487/04 ,  C07D498/04

CPC分类号： C07D498/04 ,  A61K9/0014 ,  A61K9/0048 ,  A61K9/0056 ,  A61K9/008 ,  A61K9/06 ,  A61K9/2054 ,  C07D471/04 ,  C07D471/14 ,  C07D487/04 ,  C07B2200/05

摘要： Described herein are compounds of Formula (XIII) that are TYK2 inhibitors, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders that would benefit from modulation of TYK2 activity.

公开(公告)号：US12122785B2

公开(公告)日：2024-10-22

申请号：US18160479

申请日：2023-01-27

申请人： Sudo Biosciences Limited

发明人： Anjali Pandey ,  Gregory Dietsch ,  Bhaskar Chaudhuri ,  Seetharaman Manojveer ,  Mahesh Thakkar ,  Athisayamani Jeyaraj Duraiswamy ,  Sukesh Kalva

IPC分类号： A61K31/4162 ,  C07D231/54 ,  C07D471/04 ,  C07D471/14 ,  C07D487/04 ,  C07D491/052

CPC分类号： C07D491/052 ,  C07D471/04 ,  C07D471/14 ,  C07D487/04

摘要： Described herein are compounds of Formula (I) that are TYK2 inhibitors, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders that would benefit from modulation of TYK2 activity.

公开(公告)号：US11613548B2

公开(公告)日：2023-03-28

申请号：US17737872

申请日：2022-05-05

申请人： Sudo Biosciences Limited

发明人： Anjali Pandey ,  Gregory Dietsch ,  Bhaskar Chaudhuri ,  Seetharaman Manojveer ,  Mahesh Thakkar ,  Athisayamani Jeyaraj Duraiswamy ,  Sukesh Kalva

IPC分类号： A61K31/4162 ,  C07D231/54 ,  C07D491/052 ,  C07D471/04 ,  C07D471/14 ,  C07D487/04

摘要： Described herein are compounds of Formula (XVII) that are TYK2 inhibitors, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of Using such compounds in the treatment of conditions, diseases, or disorders that would benefit from modulation of TYK2 activity.