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公开(公告)号：US08871716B2
公开(公告)日：2014-10-28
申请号：US13095763
申请日：2011-04-27
申请人： Sun-Chang Kim , Da-Jung Kim , Su-A Jang , Bong Hyun Sung , Ki-Jung Lim , Ju-Ri Shin , Young Woong Lee
发明人： Sun-Chang Kim , Da-Jung Kim , Su-A Jang , Bong Hyun Sung , Ki-Jung Lim , Ju-Ri Shin , Young Woong Lee
CPC分类号： A61K38/10
摘要： Disclosed are novel antimicrobial peptides which can promote the regeneration of skin cells, thus healing wounds. Pharmaceutical compositions comprising the peptides as active ingredients are also provided for wound healing and skin rejuvenation. The antimicrobial peptides exhibit inhibitory activity against antibiotic-resistant strains, and their antimicrobial activity is maintained without loss of structural stability even under a high salt condition. Also, being proven to promote the migration and regeneration of skin cells in mice as well as in vitro, the antimicrobial peptides may be widely used as an agent for regenerating skin cells. Further, they can find applications in various fields including the medical industry and the cosmetic industry. Hence, the novel antimicrobial peptides are anticipated to have considerable repercussions in the market for antibiotics, wound healing agents and cosmetics.
摘要翻译： 公开了可以促进皮肤细胞再生的新型抗微生物肽，从而伤口愈合。 包含肽作为活性成分的药物组合物也用于伤口愈合和皮肤年轻化。 抗菌肽对抗生素抗性菌株表现出抑制活性，即使在高盐条件下，其抗微生物活性仍保持不失结构稳定性。 此外，被证明可促进小鼠和体外皮肤细胞的迁移和再生，抗微生物肽可以广泛用作再生皮肤细胞的药剂。 此外，他们可以在包括医疗行业和化妆品行业在内的各个领域找到应用。 因此，预期新型抗菌肽在市场上对抗生素，伤口愈合剂和化妆品具有相当大的影响。
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公开(公告)号：US20120088733A1
公开(公告)日：2012-04-12
申请号：US13095763
申请日：2011-04-27
申请人： Sun-Chang Kim , Da-Jung Kim , Su-A Jang , Bong Hyun Sung , Ki-Jung Lim , Ju-Ri Shin , Young Woong Lee
发明人： Sun-Chang Kim , Da-Jung Kim , Su-A Jang , Bong Hyun Sung , Ki-Jung Lim , Ju-Ri Shin , Young Woong Lee
CPC分类号： A61K38/10
摘要： Disclosed are novel antimicrobial peptides which can promote the regeneration of skin cells, thus healing wounds. Pharmaceutical compositions comprising the peptides as active ingredients are also provided for wound healing and skin rejuvenation.The antimicrobial peptides exhibit inhibitory activity against antibiotic-resistant strains, and their antimicrobial activity is maintained without loss of structural stability even under a high salt condition. Also, being proven to promote the migration and regeneration of skin cells in mice as well as in vitro, the antimicrobial peptides may be widely used as an agent for regenerating skin cells. Further, they can find applications in various fields including the medical industry and the cosmetic industry. Hence, the novel antimicrobial peptides are anticipated to have considerable repercussions in the market for antibiotics, wound healing agents and cosmetics.
摘要翻译： 公开了可以促进皮肤细胞再生的新型抗微生物肽，从而伤口愈合。 包含肽作为活性成分的药物组合物也用于伤口愈合和皮肤年轻化。 抗菌肽对抗生素抗性菌株表现出抑制活性，即使在高盐条件下，其抗微生物活性仍保持不失结构稳定性。 此外，被证明可促进小鼠和体外皮肤细胞的迁移和再生，抗微生物肽可以广泛用作再生皮肤细胞的药剂。 此外，他们可以在包括医疗行业和化妆品行业在内的各个领域找到应用。 因此，预期新型抗菌肽在市场上对抗生素，伤口愈合剂和化妆品具有相当大的影响。
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