公开(公告)号：US20110077532A1

公开(公告)日：2011-03-31

申请号：US12891795

申请日：2010-09-27

申请人： Sunghan Kim ,  Mateo Aboy ,  James McNames

发明人： Sunghan Kim ,  Mateo Aboy ,  James McNames

IPC分类号： A61B5/021 ,  A61B5/02

CPC分类号： A61B5/0205 ,  A61B5/412 ,  A61B5/4848 ,  A61B2505/03

摘要： Methods and apparatus for determining a cardiac parameter from cardiovascular pressure signals including arterial blood pressure (ABP) and the photoplethysmographic signal to quantify the degree of amplitude modulation due to respiration and predict fluid responsiveness are disclosed. Disclosed embodiments include a method for assessing fluid responsiveness implemented in a digital computer with one or more processors comprising: (a) measuring a cardiovascular signal, and (b) computing a dynamic index predictive of fluid responsiveness from said cardiovascular signal using a nonlinear state space estimator. According to one particular embodiment, and without limitation, the nonlinear state space estimator is based on a model for cardiovascular signals such as arterial blood pressure or plethysmogram signals, and employs a marginalized particle filter to estimate a dynamic index predictive of fluid responsiveness that is substantially equivalent to a variation in pulse pressure of said cardiovascular signal.

摘要翻译： 公开了用于从心血管压力信号（包括动脉血压（ABP））和光电体积描记信号确定心脏参数的方法和装置，以量化由呼吸引起的幅度调制程度并预测流体反应性。 公开的实施例包括用于评估在具有一个或多个处理器的数字计算机中实现的流体响应性的方法，包括：（a）测量心血管信号，以及（b）使用非线性状态空间计算预测来自所述心血管信号的流体响应性的动态指数 估计。 根据一个特定实施例，非限制性地，非线性状态空间估计器基于诸如动脉血压或体积描记信号的心血管信号的模型，并且使用边缘化的粒子滤波器来估计预测流体响应性的动态指数，其基本上 相当于所述心血管信号的脉压的变化。