公开(公告)号：US20220259299A1

公开(公告)日：2022-08-18

申请号：US17413269

申请日：2019-09-25

申请人： SURFACE ONCOLOGY, INC.

发明人： Jonathan HILL ,  Scott CHAPPEL ,  Michael GLADSTONE ,  Bianka PRINZ ,  Andrew LAKE ,  Christine MILLER ,  Kerry WHITE ,  Jing HUA ,  Pamela M. HOLLAND ,  Matthew RAUSCH ,  Devapregasan MOODLEY ,  Gege TAN

IPC分类号： C07K16/24 ,  C07K16/28 ,  A61P37/04 ,  A61P35/00 ,  G01N33/574

摘要： The present disclosure relates to anti-IL-27 antibodies, and antigen-binding portions thereof. The disclosure also relates to methods for treating or ameliorating one or more symptoms of a disease, such as cancer, by administering the antibodies or antigen-binding portion thereof. The disclosure also relates to methods for detecting IL-27 in, for example, a subject or a sample.

公开(公告)号：US20220162317A1

公开(公告)日：2022-05-26

申请号：US17531380

申请日：2021-11-19

申请人： Surface Oncology, Inc.

发明人： Bianka PRINZ ,  Nadthakarn BOLAND ,  Kevin SCHUTZ ,  John BUKOWSKI ,  Jennifer SYMONDS ,  James MOHAN ,  Marisella Panduro SICHEVA

IPC分类号： C07K16/28 ,  A61P35/00 ,  A61P37/04

摘要： The invention provides anti-CD112R antibody compositions and their use in treating cancer.

公开(公告)号：US20230042258A1

公开(公告)日：2023-02-09

申请号：US17714942

申请日：2022-04-06

申请人： Surface Oncology, Inc. ,  Adimab LLC

发明人： Jonathan HILL ,  Scott CHAPPEL ,  Michael GLADSTONE ,  Bianka PRINZ ,  Andrew LAKE ,  Christine MILLER ,  Kerry WHITE ,  Jing HUA ,  Pamela M. HOLLAND ,  Matthew RAUSCH ,  Devapregasan MOODLEY

IPC分类号： C07K16/24 ,  A61P35/00 ,  A61K39/395 ,  A61K45/06 ,  G01N33/68

摘要： The present disclosure relates to anti-IL-27 antibodies, and antigen-binding portions thereof. The disclosure also relates to methods for treating or ameliorating one or more symptoms of a disease, such as cancer, by administering the antibodies or antigen-binding portion thereof. The disclosure also relates to methods for detecting IL-27 in, for example, a subject or a sample.

公开(公告)号：US20190382474A1

公开(公告)日：2019-12-19

申请号：US16362457

申请日：2019-03-22

申请人： Surface Oncology, Inc. ,  Adimab LLC

发明人： Jonathan HILL ,  Scott CHAPPEL ,  Michael GLADSTONE ,  Bianka PRINZ ,  Andrew LAKE ,  Christine MILLER ,  Kerry WHITE ,  Jing HUA ,  Pamela M. HOLLAND ,  Matthew RAUSCH ,  Devapregasan MOODLEY

IPC分类号： C07K16/24 ,  A61K45/06 ,  A61K39/395 ,  G01N33/68 ,  A61P35/00

摘要： The present disclosure relates to anti-IL-27 antibodies, and antigen-binding portions thereof. The disclosure also relates to methods for treating or ameliorating one or more symptoms of a disease, such as cancer, by administering the antibodies or antigen-binding portion thereof. The disclosure also relates to methods for detecting IL-27 in, for example, a subject or a sample.