公开(公告)号：US20140142159A1

公开(公告)日：2014-05-22

申请号：US14127675

申请日：2012-06-22

申请人： Swati Ajay Piramal ,  Muralidhara Padigaru ,  Veena R Agarwal ,  Gandhali Ashwin Deshpande

发明人： Swati Ajay Piramal ,  Muralidhara Padigaru ,  Veena R Agarwal ,  Gandhali Ashwin Deshpande

IPC分类号： C07D405/04

CPC分类号： A61K31/4025 ,  A61K45/06 ,  C07D405/04

摘要： The present invention relates to the pyrrolidine substituted with flavone derivatives, represented by the compounds of Formula (I) or a pharmaceutically acceptable salt, a solvate, a stereoisomer or a diastereoisomer thereof for use in the treatment of cancers associated with human papillomavirus. The present invention also relates to the pharmaceutical compositions containing the compounds of Formula (I) for the treatment of cancers associated with human papillomavirus.

摘要翻译： 本发明涉及用由治疗与人乳头状瘤病毒相关的癌症的式（I）化合物或其药学上可接受的盐，溶剂合物，立体异构体或非对映异构体代表的黄酮衍生物取代的吡咯烷。 本发明还涉及含有用于治疗与人乳头状瘤病毒相关的癌症的式（I）化合物的药物组合物。