公开(公告)号：US07049343B2

公开(公告)日：2006-05-23

申请号：US10344966

申请日：2001-09-07

申请人： Syed M. Ali ,  Kurt R. Brunden ,  Dario Doller ,  Brian Herbert ,  Jack B. Jiang ,  Amy Jordan

发明人： Syed M. Ali ,  Kurt R. Brunden ,  Dario Doller ,  Brian Herbert ,  Jack B. Jiang ,  Amy Jordan

IPC分类号： A01N74/34 ,  A61K31/175

CPC分类号： C07C243/38 ,  C07C243/22 ,  C07C243/28 ,  C07C243/34 ,  C07C255/24 ,  C07C255/66 ,  C07C259/06 ,  C07C327/44 ,  C07D231/08

摘要： A method for the inhibition of high affinity glycine transporters, compounds that inhibit these transporters; pharmaceutically active compositions comprising such compounds; and the use of such compounds either as above, or in formulations for the control or prevention of disease states in which glycine is involved are disclosed.