公开(公告)号：US20110076192A1

公开(公告)日：2011-03-31

申请号：US12893742

申请日：2010-09-29

申请人： Simon ROBITAILLE ,  Sylvie DUFRESNE ,  Jean-Martin VALLIERES ,  Cynthia MARTEL ,  Helene LEBLOND ,  Nancy DASSIE ,  Marie-Christine GAGNE ,  Karine MARTEL ,  Claudia BEDARD ,  Bruno TREMBLAY

发明人： Simon ROBITAILLE ,  Sylvie DUFRESNE ,  Jean-Martin VALLIERES ,  Cynthia MARTEL ,  Helene LEBLOND ,  Nancy DASSIE ,  Marie-Christine GAGNE ,  Karine MARTEL ,  Claudia BEDARD ,  Bruno TREMBLAY

IPC分类号： A61L2/16 ,  B65D90/02

CPC分类号： A61L2/202 ,  A61L2/20 ,  A61L2/208 ,  A61L2202/122 ,  A61L2202/13 ,  A61L2202/14 ,  A61L2202/24 ,  B65D23/001

摘要： A method of sterilizing an article by sequentially exposing the article to hydrogen peroxide and ozone is disclosed. The article is exposed under vacuum first to an evaporated aqueous solution of hydrogen peroxide and subsequently to an ozone containing gas. The exposure is carried out without reducing the water vapor content of the sterilization atmosphere, the water vapor content being derived from the aqueous solvent of the hydrogen peroxide solution and from the decomposition of the hydrogen peroxide into water and oxygen. The complete sterilization process is carried out while the chamber remains sealed and without removal of any component of the sterilization atmosphere. For this purpose, the chamber is initially evacuated to a first vacuum pressure sufficient to cause evaporation of the aqueous hydrogen peroxide at the temperature of the chamber atmosphere. The chamber is then sealed for the remainder of the sterilization process and during all sterilant injection cycles. Keeping the chamber sealed and maintaining the hydrogen peroxide and its decomposition products in the chamber for the subsequent ozone sterilization step results in a synergistic increase in the sterilization efficiency and allows for the use of much lower sterilant amounts and sterilization cycle times than would be expected from using hydrogen peroxide and ozone in combination.

摘要翻译： 公开了通过将制品依次暴露于过氧化氢和臭氧来对制品进行灭菌的方法。 将该制品首先在真空下暴露于蒸发的过氧化氢水溶液中，随后暴露于含臭氧气体。 曝光是在不降低灭菌气氛的水蒸气含量的情况下进行的，水蒸汽含量来自过氧化氢溶液的水性溶剂和由过氧化氢分解成水和氧气。 在室保持密封且不除去灭菌气氛的任何成分的情况下完成灭菌过程。 为此，腔室最初被抽空到第一真空压力，足以在室气氛的温度下引起过氧化氢水溶液的蒸发。 然后将腔室密封用于灭菌过程的剩余部分和所有灭菌剂注射循环期间。 将室密封并将过氧化氢及其分解产物保持在室中用于随后的臭氧消毒步骤导致灭菌效率的协同增加，并允许使用比预期的更低的杀菌剂量和灭菌循环时间 使用过氧化氢和臭氧组合使用。

公开(公告)号：US20130236355A1

公开(公告)日：2013-09-12

申请号：US13779132

申请日：2013-02-27

申请人： Sylvie DUFRESNE ,  Cynthia MARTEL ,  Helene LEBLOND ,  Nancy DASSIE ,  Karine MARTEL

发明人： Sylvie DUFRESNE ,  Cynthia MARTEL ,  Helene LEBLOND ,  Nancy DASSIE ,  Karine MARTEL

IPC分类号： A61L2/20

CPC分类号： A61L2/202 ,  A61L2/20 ,  A61L2/208 ,  A61L2202/122 ,  A61L2202/13 ,  A61L2202/14 ,  A61L2202/24 ,  B65D23/001

摘要： Disclosed is a method of sterilizing an article by sequentially exposing the article under vacuum first to a gaseous conditioning agent for forming radicals and then to a sterilant. The preferred conditioning agent is hydrogen peroxide and the preferred sterilant is ozone. The chamber is initially evacuated to a first vacuum pressure and then sealed for the remainder of the sterilization process and during all sterilant injection cycles, without removal of any component of the sterilization atmosphere, which means without any measures to reduce the water vapor content. Keeping the chamber sealed and maintaining the conditioning agent and the radicals generated thereby in the chamber for the sterilization with sterilant results in a synergistic increase in the sterilization efficiency and allows for the use of much lower sterilant amounts and sterilization cycle times than would be expected from using the conditioning agent and the sterilant in combination.

摘要翻译： 公开了一种通过在真空下首先将制品先暴露于用于形成自由基的气态调节剂，然后到灭菌剂来对制品进行灭菌的方法。 优选的调理剂是过氧化氢，优选的灭菌剂是臭氧。 该腔室最初被抽空到第一真空压力，然后密封灭菌过程的剩余部分，并且在所有灭菌剂注射循环期间，不除去灭菌气氛的任何成分，这意味着没有任何措施来减少水蒸汽含量。 保持室密封并保持调理剂和由此产生的自由基在灭菌器灭菌室中导致灭菌效率的协同增加，并允许使用比预期的更低的杀菌剂量和灭菌循环时间 使用调理剂和灭菌剂组合使用。