公开(公告)号：US10668260B2

公开(公告)日：2020-06-02

申请号：US14774385

申请日：2014-03-11

申请人： TAKEDA PHARMACEUTICAL COMPANY LIMITED

发明人： Yoshihiro Omachi ,  Yasuhiro Hiraishi ,  Masami Kusaka ,  Shigehiro Asano ,  Masao Nagao

IPC分类号： A61M37/00 ,  A61K9/00 ,  A61K9/70 ,  B29C45/00 ,  B29C45/16 ,  B29K101/12 ,  B29L9/00 ,  B29L31/00

摘要： The present invention provides a microneedle patch which can solve the problem that microneedle production is difficult and requires high accuracy, the problem that time and mental burdens on a health professional and a patient are large, and the problem caused by compounding a plurality of drugs. The microneedle patch comprises a large number of drug-carrying microprojections 4 erected on one support sheet, each microprojection 4 having a drug layer 5 soluble in vivo at its top part and having an intermediate layer 6 under the drug layer 5, the intermediate layer 6 containing a polymeric substance for adhesion of the drug layer 5 to the support sheet, the drug layer 5 at the top part of the microprojection 4 containing a single drug, the microprojections 4 holding difference types of drugs being arranged together on the support sheet 2.