公开(公告)号：US20200377458A1

公开(公告)日：2020-12-03

申请号：US16496530

申请日：2017-03-29

Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED

Inventor： Yoshito TERAO ,  Masashi TAKAHASHI ,  Ryoma HARA ,  Kousuke HIDAKA ,  Hideki FURUKAWA ,  Takeshi YAMASAKI ,  Shizuo KASAl

IPC: C07D209/96 ,  C07D401/12 ,  A61P3/10 ,  A61P9/04 ,  C07D471/10 ,  C07D491/052 ,  C07D403/12

Abstract: The present invention aims to provide a heterocyclic compound having an IP6K inhibitory action and expected to be useful as a prophylactic or therapeutic agent for—diseases such as cardiac failure, diabetes and the like. A compound represented by the formula (I): wherein each symbol is as defined in the SPECIFICATION, or a salt thereof has an IP6K inhibitory action and is expected to be useful as a prophylactic or therapeutic agent for diseases such as cardiac failure, diabetes and the like.

公开(公告)号：US20150018373A1

公开(公告)日：2015-01-15

申请号：US14325564

申请日：2014-07-08

Applicant: Takeda Pharmaceutical Company Limited

Inventor： Hideyuki IGAWA ,  Masashi TAKAHASHI ,  Keiko KAKEGAWA ,  Minoru IKOMA ,  Jumpei AIDA

IPC: C07D401/04 ,  C07D405/14 ,  C07D417/14 ,  C07D401/14 ,  C07D409/14

CPC classification number: C07D401/04 ,  C07D401/14 ,  C07D405/14 ,  C07D409/14 ,  C07D417/14

Abstract: Provided is a compound having a melanin-concentrating hormone receptor antagonistic action and is useful as an agent for the prophylaxis or treatment of obesity and the like. A compound represented by the formula (I): wherein each symbol is as defined in the specification, or a salt thereof.

Abstract translation: 提供具有黑色素浓集激素受体拮抗作用的化合物，并且可用作预防或治疗肥胖症等的药剂。 由式（I）表示的化合物或其盐，其中每个符号如说明书中所定义。