公开(公告)号：US20180376048A1

公开(公告)日：2018-12-27

申请号：US16015363

申请日：2018-06-22

Applicant: TECAN TRADING AG

Inventor： Markus SCHÜRF ,  Frank MÜNCHOW ,  Christian OBERDANNER ,  Alexander KASER

IPC: H04N5/235 ,  H04N5/232 ,  H04N5/265

Abstract: An imaging system and method are provided in which a well of a microplate 050 is imaged by a camera 110 comprising magnification optics 112. The camera is controlled to acquire a series of images of the well with different exposures. The series of images comprise a base image with a base exposure and at least one further image with a larger exposure than the base exposure. The series of images are then merged into an output image which comprises in a center region of the well image content from the base image and at a peripheral region of the well image content from the at least one further image. Advantageously, the output image may allow for better assaying or analysis of the samples in the well than any of the individual images.

公开(公告)号：US20160011048A1

公开(公告)日：2016-01-14

申请号：US14794316

申请日：2015-07-08

Applicant: TECAN Trading AG

Inventor： Lutz NIGGL ,  Andreas ERLBACHER ,  Frank MÜNCHOW

IPC: G01J3/18 ,  G01J3/42 ,  G01J3/06

CPC classification number: G01J3/18 ,  G01J3/06 ,  G01J3/42 ,  G01J2003/1204 ,  G01J2003/1213 ,  G01J2003/1217 ,  G01N21/253 ,  G01N21/31 ,  G01N35/028 ,  G01N2021/3174 ,  G01N2201/084

Abstract: A spectrometer (1) comprises a light source (2), a monochromator (3) with at least one diffraction grating (4), a monochromator housing (5), an order sorting filter (7), a microplate receptacle (12) and a controller (6). The order sorting filter (7) of the spectrometer (1) comprises a substrate (23), a first optical thin film (24) and a second optical thin film (25), wherein, in a spatially partly overlapping and interference-free manner, the first optical thin film (24) is arranged on a first surface (26) and the second optical thin film (25) is arranged on a second surface (27) of the substrate (23). A spectrometer (1) equipped with a respective order sorting filter is used in a scanning method for detecting the absorption spectrum of samples examined in wells (14) of microplates (13).

Abstract translation: 光谱仪（1）包括光源（2），具有至少一个衍射光栅（4）的单色仪（3），单色仪外壳（5），订单分类过滤器（7），微板容器（12）和 控制器（6）。 光谱仪（1）的顺序分选滤光器（7）包括基板（23），第一光学薄膜（24）和第二光学薄膜（25），其中在空间上部分重叠和无干扰的方式 第一光学薄膜（24）布置在第一表面（26）上，第二光学薄膜（25）被布置在基板（23）的第二表面（27）上。 在用于检测在微孔板（13）的孔（14）中检测的样品的吸收光谱的扫描方法中，使用装备有相应的顺序分选过滤器的光谱仪（1）。