Patent search ap:("TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION") AND inv:"Jennifer GORDON" Page 1

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发明申请
CRISPR/CAS9 SYSTEM AS AN AGENT FOR INHIBITION OF POLYOMA JC INFECTION 有权

公开(公告)号：US20220380812A1

公开(公告)日：2022-12-01

申请号：US17776120

申请日：2020-11-11

Applicant: TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION

Inventor： Kamel KHALILI , Hassen S. WOLLEBO , Jennifer GORDON , Ilker K. SARIYER

IPC: C12N15/90 , C12N9/22 , C12N15/11

Abstract: Provided herein are gene editing compositions and methods that effectively modulate and/or edit a JCV genome. The effective modulation and/or editing is, in an aspect, achieved by gene editing compositions targeting a NCCR region, an early coding gene, and/or a late coding gene.

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