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公开(公告)号：US11807642B2
公开(公告)日：2023-11-07
申请号：US17541682
申请日：2021-12-03
Inventor： Benjamin E. Blass , Daniel J. Canney , Kevin M. Blattner
IPC: C07D487/04
CPC classification number: C07D487/04
Abstract: Pharmaceutical compositions of the invention comprise functionalized lactone derivatives having a disease-modifying action in the treatment of diseases associated with dysregulation of 5-hydroxytryptamine receptor 7 activity.
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公开(公告)号：US11319327B2
公开(公告)日：2022-05-03
申请号：US17015696
申请日：2020-09-09
Inventor： Daniel J. Canney , Benjamin E. Blass , Kevin M. Blattner , Douglas A. Pippin
IPC: C07D491/107 , C07D221/00 , C07D295/073 , C07D309/08 , C07D493/10 , C07D513/04 , C07F7/10 , C07D413/10
Abstract: Pharmaceutical compositions of the invention comprise functionalized lactone derivatives having a disease-modifying action in the treatment of diseases associated with dysregulation of 5-hydroxytryptamine receptor 7 activity.
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公开(公告)号：US20200317648A1
公开(公告)日：2020-10-08
申请号：US16861075
申请日：2020-04-28
Inventor： Daniel J. Canney , Benjamin E. Blass , Rong Gao , Magid Abou-Gharbia
IPC: C07D405/12 , C07D405/06 , C07D307/94 , C07D307/33
Abstract: Pharmaceutical compositions of the invention comprise functionalized lactone derivatives having a disease-modifying action in the treatment of diseases associated with dysregulation of 5-hydroxytryptamine receptor 7 activity.
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公开(公告)号：US10544117B2
公开(公告)日：2020-01-28
申请号：US15510152
申请日：2015-09-10
Inventor： Daniel J. Canney , Benjamin E. Blass , Rong Gao , Magid Abou-Gharbia
IPC: C07D405/12 , A61K31/496 , C07D307/33 , C07D307/94 , C07D405/06
Abstract: Pharmaceutical compositions of the invention comprise functionalized lactone derivatives of formula (I) having a disease-modifying action in the treatment of diseases associated with dysregulation of 5-hydroxytryptamine receptor 7 activity.
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公开(公告)号：US10239868B2
公开(公告)日：2019-03-26
申请号：US15716752
申请日：2017-09-27
Inventor： Daniel J. Canney , Benjamin E. Blass , Rong Gao , Magid Abou-Gharbia
IPC: C07D405/12 , C07D405/06 , C07D307/94 , C07D307/33
Abstract: Pharmaceutical compositions of the invention comprise functionalized lactone derivatives having a disease-modifying action in the treatment of diseases associated with dysregulation of 5-hydroxytryptamine receptor 7 activity.
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Patent Agency Ranking
6.发明申请DISUBSTITUTED OXAZOLIDIN-2-ONES 5-HYDROXYTRYPTAMINE RECEPTOR 2B ACTIVITY MODULATORS 有权分析的氧杂环丁烷-2-酮5-羟基嘧啶受体2B活性调节剂公开(公告)号：US20150291539A1
公开(公告)日：2015-10-15
申请号：US14646290
申请日：2013-11-26
Inventor： Daniel J. Canney , Richie R. Bhandare , Benjamin E. Blass , Magid Abou-Gharbia
IPC: C07D263/20
CPC classification number: C07D263/20 , C07D263/24 , C07D413/06
Abstract: Pharmaceutical compositions of the invention comprise disubstituted oxazolidin-2-ones derivatives having a disease-modifying action in the treatment of diseases associated with dysregulation of 5-hydroxytryptamine receptor 2b activity.
Abstract translation: 本发明的药物组合物包含在治疗与5-羟色胺受体2b活性失调相关的疾病中具有疾病改变作用的二取代的恶唑烷-2-酮衍生物。
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公开(公告)号：US20220306629A1
公开(公告)日：2022-09-29
申请号：US17054468
申请日：2019-05-10
Inventor： Daniel J. Canney , Benjamin E. Blass , Kevin M. Blattner , Douglas A. Pippin
IPC: C07D471/10 , C07D487/04 , C07D401/06
Abstract: Pharmaceutical compositions of the invention comprise functionalized lactam derivatives of formula (I) having a disease-modifying action in the treatment of diseases associated with dysregulation of 5-hydroxytryptamine receptor 7 activity. A is selected from a group consisting of (group) and (group)
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公开(公告)号：US11220505B2
公开(公告)日：2022-01-11
申请号：US16496065
申请日：2018-03-15
Inventor： Benjamin E. Blass , Daniel J. Canney , Kevin M. Blattner
IPC: C07D487/04
Abstract: Pharmaceutical compositions of the invention comprise functionalized lactone derivatives having a disease-modifying action in the treatment of diseases associated with dysregulation of 5-hydroxytryptamine receptor 7 activity.
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公开(公告)号：US10858368B2
公开(公告)日：2020-12-08
申请号：US16349811
申请日：2017-11-15
Inventor： Daniel J. Canney , Benjamin E. Blass , Kevin M. Blattner , Douglas A. Pippin
IPC: C07D491/107 , C07D221/00 , C07D295/073 , C07D309/08 , C07D413/10 , C07D493/10 , C07D513/04 , C07F7/10
Abstract: Pharmaceutical compositions of the invention comprise functionalized lactone derivatives having a disease-modifying action in the treatment of diseases associated with dysregulation of 5-hydroxytryptamine receptor 7 activity.
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公开(公告)号：US10287274B2
公开(公告)日：2019-05-14
申请号：US15716773
申请日：2017-09-27
Inventor： Daniel J. Canney , Benjamin E. Blass , Rong Gao , Magid Abou-Gharbia
IPC: C07D405/12 , C07D405/06 , C07D307/94 , C07D307/33
Abstract: Pharmaceutical compositions of the invention comprise functionalized lactone derivatives having a disease-modifying action in the treatment of diseases associated with dysregulation of 5-hydroxytryptamine receptor 7 activity.
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