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公开(公告)号:US20240239903A1
公开(公告)日:2024-07-18
申请号:US18409571
申请日:2024-01-10
Inventor: Linda DONNELLY , Xiaofeng QI , Xiaochun LI
CPC classification number: C07K16/2863 , A61K45/06 , G01N33/6893 , C07K2317/21 , C07K2317/24 , C07K2317/76 , G01N2333/705 , G01N2800/7057
Abstract: Disclosures herein are directed to antibodies and epitope binding agents that specifically bind to the extracellular domain of Patched-1 and compositions thereof for use in clinical and non-clinical applications. Also provided are methods to treat and/or prevent Hedgehog pathway related disorders.