公开(公告)号：US10589096B2

公开(公告)日：2020-03-17

申请号：US15496444

申请日：2017-04-25

Applicant: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM

Inventor： Nitin Tandon

IPC: A61N1/36 ,  A61N1/05 ,  A61B5/00 ,  A61B8/08 ,  A61B6/00 ,  A61B5/055 ,  A61B6/03

Abstract: This invention relates generally to systems and methods for multifocal direct brain stimulation to enhance cognitive processing, such as but not limited to stimulation-induced modulation of memory.

公开(公告)号：US11497401B2

公开(公告)日：2022-11-15

申请号：US16212938

申请日：2018-12-07

Applicant: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM

Inventor： Nitin Tandon ,  Christopher Conner ,  Thomas A. Pieters ,  Cihan Mehmet Kadipasaoglu

IPC: A61B5/00 ,  A61B5/055 ,  A61B6/03 ,  A61B6/12 ,  A61B5/06 ,  A61B6/00 ,  A61B5/369 ,  A61B5/37 ,  G06T15/04 ,  A61B34/10 ,  A61B34/20 ,  A61B5/384

Abstract: This invention relates generally to methods for localization and visualization of implanted electrodes and penetrating probes in the brain in 3D space with consideration of functional brain anatomy. Particularly, this invention relates to precise and sophisticated methods of localizing and visualizing implanted electrodes to the cortical surface and/or topological volumes of a patient's brain using 3D modeling, and more particularly to methods of accurately mapping implanted electrodes to the cortical topology and/or associated topological volumes of a patient's brain, such as, for example, by utilizing recursive grid partitioning on a manipulable virtual replicate of a patient's brain. This invention further relates to methods of surgical intervention utilizing accurate cortical surface modeling and/or topological volume modeling of a patient's brain for targeted placement of electrodes and/or utilization thereof for surgical intervention in the placement of catheters or other probes into it.