公开(公告)号：US20130302245A1

公开(公告)日：2013-11-14

申请号：US13864986

申请日：2013-04-17

Applicant: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM

Inventor： David J. YANG ,  Chang-sok OH ,  Saady KOHANIM ,  Dongfang YU ,  Richard MENDEZ ,  E. Edmund KIM

IPC: A61K51/04 ,  C07F13/00

CPC classification number: A61K51/0497 ,  A61K31/165 ,  C07C235/34 ,  C07F13/00 ,  C07F13/005

Abstract: Compositions and methods for imaging and for chemotherapy and radiotherapy are disclosed. More particularly, the invention concerns agents comprising a targeting moeity comprising a beta-adrenergic receptor targeting compound conjugated or embedded with ethylenediamine. The present invention also concerns methods of application of such agents for imaging and treatment of cardiovascular diseases, and kits for preparing a radiolabeled therapeutic or diagnostic agent.