公开(公告)号：US20190270705A1

公开(公告)日：2019-09-05

申请号：US16461793

申请日：2017-11-20

Applicant: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM

Inventor： Fernanda Laezza ,  Jia Zhou ,  Zhiqing Liu ,  Syed Ali

IPC: C07D207/16 ,  C07D417/12 ,  C07D413/12 ,  C07C237/52

Abstract: The present invention relates to novel small molecule modulators of Nav1.6 channels of the general formulae (I), (II), (III) and (IV), and the uses thereof.

公开(公告)号：US10889543B2

公开(公告)日：2021-01-12

申请号：US16461793

申请日：2017-11-20

Applicant: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM

Inventor： Fernanda Laezza ,  Jia Zhou ,  Zhiqing Liu ,  Syed Ali

IPC: C07D207/16 ,  C07C237/52 ,  C07D413/12 ,  C07D417/12 ,  A61K31/5377 ,  A61K38/18 ,  C07K5/087 ,  A61K31/401 ,  C07K5/107 ,  A61K45/06 ,  C07K5/083 ,  A61K31/427

Abstract: The present invention relates to novel small molecule modulators of Nav1.6 channels of the general formulae (I), (II), (III) and (IV), and the uses thereof.