专利检索 ap:("THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM" OR "THE GEORGE WASHINGTON UNIVERSITY") AND inv:"Xiujie SUN" 第 1 页

1.

发明公开
NOVEL DDR1 ANTIBODIES AND USES THEREOF 审中-公开

公开(公告)号：US20230235078A1

公开(公告)日：2023-07-27

申请号：US18176072

申请日：2023-02-28

申请人： The BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM , THE GEORGE WASHINGTON UNIVERSITY

发明人： Ningyan ZHANG , Zhiqiang AN , Hui DENG , Xiujie SUN , Rong LI

IPC分类号： C07K16/28 , C12N15/63 , A61P35/00

CPC分类号： C07K16/2896 , C12N15/63 , A61P35/00 , C07K2317/20 , C07K2317/565

摘要： The present disclosure relates to antibodies binding to tumor discoidin domain receptor 1 (DDR1) and the uses of the antibodies in detecting and treating cancer.

2.

发明申请
NOVEL DDR1 ANTIBODIES AND USES THEREOF 有权

公开(公告)号：US20230130372A1

公开(公告)日：2023-04-27

申请号：US17757510

申请日：2020-12-17

申请人： THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM , THE GEORGE WASHINGTON UNIVERSITY

发明人： Ningyan ZHANG , Zhiqiang AN , Hui DENG , Xiujie SUN , Rong LI

IPC分类号： C07K16/28 , C12N15/63 , A61P35/00

摘要： The present disclosure relates to antibodies binding to tumor discoidin domain receptor 1 (DDR1) and the uses of the antibodies in detecting and treating cancer. Thus, in one aspect, the present disclosure provides an isolated monoclonal antibody or an antigen-binding fragment thereof that binds specifically to DDR1. In certain embodiments, the antibody or antigen-binding fragment, when bound to DDR1, modulates the activity of DDR1, i.e., suppresses DDR1.