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公开(公告)号:US20240287175A1
公开(公告)日:2024-08-29
申请号:US18526952
申请日:2023-12-01
申请人: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY , THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS
发明人: Anton Wyss-Coray , John Vincent Pluvinage , Michael C. Bassik , Michael Haney , Benjamin Smith , Carolyn Bertozzi
IPC分类号: C07K16/28 , A61K38/47 , A61K39/00 , A61K39/395 , A61K47/68 , A61M25/00 , A61P25/28 , C12N9/24
CPC分类号: C07K16/2803 , A61K38/47 , A61K39/001113 , A61K39/3955 , A61K47/6815 , A61K47/6849 , A61P25/28 , C12N9/2402 , C12Y302/01018 , A61K2039/505 , A61M25/0097 , C07K2317/76 , C07K2317/77
摘要: Provided herein are compositions, methods, kits and systems for treating cells, tissues and subjects to alter age-related biology (e.g., to study or to treat age-related diseases and conditions). In particular, provided herein are compositions, methods, and uses for inhibition or modification of sialic acid or its cognate receptor to restore phagocytosis in aged cells.
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公开(公告)号:US20200317778A1
公开(公告)日:2020-10-08
申请号:US16956339
申请日:2018-12-21
申请人: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY , THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS
发明人: Anton Wyss-Coray , John Vincent Pluvinage , Michael C. Bassik , Michael Haney , Benjamin Smith , Carolyn Bertozzi
摘要: Provided herein are compositions, methods, kits and systems for treating cells, tissues and subjects to alter age-related biology (e.g., to study or to treat age-related diseases and conditions). In particular, provided herein are compositions, methods, and uses for inhibition or modification of sialic acid or its cognate receptor to restore phagocytosis in aged cells.
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公开(公告)号:US11891442B2
公开(公告)日:2024-02-06
申请号:US16956339
申请日:2018-12-21
申请人: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY , THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS
发明人: Anton Wyss-Coray , John Vincent Pluvinage , Michael C. Bassik , Michael Haney , Benjamin Smith , Carolyn Bertozzi
IPC分类号: C07K16/28 , A61P25/28 , A61K39/395 , A61K39/00 , A61K38/47 , C12N9/24 , A61K47/68 , A61M25/00
CPC分类号: C07K16/2803 , A61K38/47 , A61K39/001113 , A61K39/3955 , A61K47/6815 , A61K47/6849 , A61P25/28 , C12N9/2402 , C12Y302/01018 , A61K2039/505 , A61M25/0097 , C07K2317/76 , C07K2317/77
摘要: Provided herein are compositions, methods, kits and systems for treating cells, tissues and subjects to alter age-related biology (e.g., to study or to treat age-related diseases and conditions). In particular, provided herein are compositions, methods, and uses for inhibition or modification of sialic acid or its cognate receptor to restore phagocytosis in aged cells.
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