公开(公告)号：US20240094207A1

公开(公告)日：2024-03-21

申请号：US18448425

申请日：2023-08-11

申请人： THE JOHNS HOPKINS UNIVERSITY ,  CDI LABORATORIES, INC.

发明人： Ignacio Pino ,  Heng Zhu ,  Jiang Qian ,  Yi Huang

IPC分类号： G01N33/574 ,  G01N33/564 ,  G16H50/20

CPC分类号： G01N33/57423 ,  G01N33/564 ,  G16H50/20

摘要： Biomarkers to screen for, identify, and/or characterize lung cancer in a subject are disclosed. Also disclosed herein are methods for distinguishing lung cancer from another disease. Also disclosed herein are methods for detecting metastasis of a lung cancer in a subject. Also disclosed herein are substrates, arrays, and reagents for use in the methods, and methods of their preparation.

公开(公告)号：US20230272339A1

公开(公告)日：2023-08-31

申请号：US18310048

申请日：2023-05-01

申请人： The Johns Hopkins University

发明人： Mandeep SINGH ,  Seth Blackshaw ,  Robert Johnston ,  Jiang Qian ,  Ying Liu

IPC分类号： C12N5/0793

CPC分类号： C12N5/062 ,  C12N2513/00 ,  C12N2509/00

摘要： The present disclosure provides methods for generating retinal cell clusters for use in cellular component transfer therapy, retinal cell clusters generated by such methods, and compositions comprising such retinal cell clusters. The present disclosure also provides uses of the retinal cell clusters and compositions comprising thereof for preventing and/or treating inherited retinal degenerative diseases.