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公开(公告)号：US10111937B2
公开(公告)日：2018-10-30
申请号：US15095685
申请日：2016-04-11
Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
Inventor： James A. Shayman , Akira Abe , Robert Kelly , Jessica Kollmeyer , Ye Lu
IPC: C07K14/755 , A61K38/45 , C12Q1/44 , A61K38/46 , G01N33/68
Abstract: The present invention is directed to methods for diagnosis and treatment of systemic lupus erythematosus and drug-induced systemic lupus erythematosus. More specifically, the specification describes methods using a lysosomal phospholipase A2 in methods for the diagnosis and treatment of autoimmune disorders such as systemic lupus erythematosus and drug-induced systemic lupus erythematosus.
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2.发明申请Lysosomal Phospholipase A2 (LPLA2) Activity as a Diagnostic and Therapeutic Target for Identifying and Treating Systemic Lupus Erythematosus 审中-公开溶酶体磷脂酶A2（LPLA2）作为鉴定和治疗系统性红斑狼疮的诊断和治疗靶标的活性公开(公告)号：US20160317626A1
公开(公告)日：2016-11-03
申请号：US15095685
申请日：2016-04-11
Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
Inventor： James A. Shayman , Akira Abe , Robert Kelly , Jessica Kollmeyer , Ye Lu
CPC classification number: A61K38/45 , A61K38/465 , C12Q1/44 , C12Y203/01 , C12Y301/01005 , G01N33/6854 , G01N2333/91051 , G01N2333/918 , G01N2800/104 , G01N2800/56
Abstract: The present invention is directed to methods for diagnosis and treatment of systemic lupus erythematosus and drug-induced systemic lupus erythematosus. More specifically, the specification describes methods using a lysosomal phospholipase A2 in methods for the diagnosis and treatment of autoimmune disorders such as systemic lupus erythematosus and drug-induced systemic lupus erythematosus.
Abstract translation: 本发明涉及用于诊断和治疗系统性红斑狼疮和药物诱发的系统性红斑狼疮的方法。 更具体地，本说明书描述了在诊断和治疗诸如系统性红斑狼疮和药物诱发的系统性红斑狼疮的自身免疫疾病的方法中使用溶酶体磷脂酶A2的方法。
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