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公开(公告)号：US11020470B2
公开(公告)日：2021-06-01
申请号：US15566069
申请日：2016-04-12
Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
Inventor： Fei Wen , Eshita Khera , Brett Dallas Hill , Syed Rizvi
IPC: A61K39/12 , C12N15/81 , A61K39/145 , A61K39/21 , C07K14/395 , A61K39/00
Abstract: Provided herein are membrane enveloped virus-like particles (VLPs), and methods of use and synthesis thereof. In particular, yeast-cell-derived VLPs are provided that comprise surface-displayed glycoproteins and/or multiple virally-derived proteins.
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