专利检索 ap:("THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY") AND inv:"KENNETH V.N. ESGUERRA" 第 1 页

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发明申请
METHOD FOR PRODUCING AN ARENE WITH AN AROMATIC C-N BOND ORTHO TO AN AROMATIC C-O BOND 有权
标题翻译：用芳香C-N粘结剂生产ARA的芳香族C-O键的方法

公开(公告)号：US20170066711A1

公开(公告)日：2017-03-09

申请号：US15255957

申请日：2016-09-02

申请人： THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY

发明人： JEAN-PHILIP LUMB , KENNETH V.N. ESGUERRA

IPC分类号： C07C249/02 , C07C213/08 , C07C45/29 , C07D265/36 , C07D263/56

CPC分类号： C07C249/02 , C07C46/08 , C07C213/08 , C07C2601/14 , C07C2601/16 , C07C2602/10 , C07D263/56 , C07D265/36 , C07F7/00 , C07F7/0812 , C07C50/02 , C07C50/08 , C07C50/28 , C07C50/12 , C07C50/32 , C07C50/24

摘要： A method for producing an arene with an aromatic C—N bond ortho to an aromatic C—O bond from a hydroxy arene comprising said aromatic C—O bond is provided. This method comprising the steps a) ortho-oxygenating the hydroxy arene to produce an ortho-quinone, b) condensating the ortho-quinone with a nitrogen nucleophile to generate a compound of Formula (IVa) or (IVb), and c) allowing 1,5-hydrogen atom shift of the compound of Formula (IVa) or (IVb), thereby producing arenes with a C—N bond ortho to a C—O bond of Formula (Va) and (Vb), respectively: