公开(公告)号：US20210236434A1

公开(公告)日：2021-08-05

申请号：US17160836

申请日：2021-01-28

Applicant: THE TEXAS A&M UNIVERSITY SYSTEM

Inventor： Naga Venkata Ravi Kumar MAJETI ,  Raghu GANUGULA ,  Meenakshi ARORA ,  Dianxiong ZOU

IPC: A61K9/51 ,  A61K31/282

Abstract: The present disclosure provides nanoparticle compositions comprising i) a polymeric nanoparticle, ii) one or more ligands conjugated to the polymeric nanoparticle, and iii) urolithin A. The disclosure also provides methods and pharmaceutical compositions comprising the nanoparticle compositions for use in treating patients with various disease states.

公开(公告)号：US20230201369A1

公开(公告)日：2023-06-29

申请号：US17996562

申请日：2021-04-29

Applicant: THE TEXAS A&M UNIVERSITY SYSTEM

Inventor： Shoshana EITAN ,  Naga Venkata Ravi Kumar MAJETI

IPC: A61K47/69 ,  A61K31/485 ,  A61P25/36

CPC classification number: A61K47/6937 ,  A61K31/485 ,  A61P25/36 ,  A61K9/0053

Abstract: The present disclosure provides nanoparticle compositions comprising i) a polymeric nanoparticle, ii) one or more ligands conjugated to the polymeric nanoparticle, and iii) naloxone. The disclosure also provides methods and pharmaceutical compositions comprising the nanoparticle compositions for use in treating patients with various disease states.