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1.
公开(公告)号:US11857571B2
公开(公告)日:2024-01-02
申请号:US16994795
申请日:2020-08-17
发明人: Charles Sentman , Michael Battles
CPC分类号: A61K35/17 , A61K47/6835 , A61K51/1045 , A61K51/1096 , A61P35/00 , C07K16/2809 , C07K16/2833 , C07K16/2851 , A61K2039/505 , C07K2317/31 , C07K2317/622 , C07K2319/03
摘要: Antigen binding fragments, chimeric antigen receptors, and bi-specific T-cell engagers having specificity for MICA and methods for using the same in the diagnosis and treatment of disorders associated with MICA and/or MICB expression are provided.
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2.
公开(公告)号:US10744157B2
公开(公告)日:2020-08-18
申请号:US15561748
申请日:2016-03-25
发明人: Charles Sentman , Michael Battles
摘要: Antigen binding fragments, chimeric antigen receptors, and bi-specific T-cell engagers having specificity for MICA and methods for using the same in the diagnosis and treatment of disorders associated with MICA and/or MICB expression are provided.
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