专利检索 ap:("THE TRUSTEES OF DARTMOUTH COLLEGE" OR "KING'S COLLEGE LONDON") AND inv:"Isabelle LeMERCIER" 第 1 页

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发明申请
VISTA ANTAGONIST AND METHODS OF USE 审中-公开

公开(公告)号：US20200093902A1

公开(公告)日：2020-03-26

申请号：US16669552

申请日：2019-10-31

申请人： THE TRUSTEES OF DARTMOUTH COLLEGE , KING'S COLLEGE LONDON

发明人： Randolph J. NOELLE , Sabrina CEERAZ , Isabelle LeMERCIER , Elizabeth NOWAK , Janet LINES , Li WANG , Mark SPALLER

IPC分类号： A61K39/00 , C07K16/28 , G01N33/566 , C07K7/08 , A61K45/06

摘要： The present invention is directed to a peptide, multimer, conjugate, analog, derivative or mimetic thereof that inhibits the activity of VISTA. The invention further contemplates therapeutic use of the VISTA antagonist peptide, multimer, conjugate, derivative or mimetic thereof, including treating or preventing cancer, bacterial infections, viral infections, parasitic infections and fungal infections, as well as research uses of the antagonist.